Cephea Valve Technologies, Inc.

Abbott Cardiovascular Systems, Inc.

Abbott Laboratories Vascular Enterprises Limited

Edwards Lifesciences Ag

Sympara Medical, Inc.

Jomed Gmbh

Other

Abbott Laboratories Corporation

Evalve, Inc.

Heraeus Precious Metals Gmbh & Co. Kg

Abbott Ireland

Randolf Von Oepen

Sean A McNiven

Francisco Valencia

Kevin Joe Ehrenreich

Gerd Seibold

Ken C Salvador

Travis Richard Yribarren

Ib Erling Joergensen

William E Webler, Jr

Yongjin Xie

Li Fu Chen

Jan Otto Solem

Kenneth J Michlitsch

Marc Gianotti

Silvio Schaffner

Rommel Lumauig

Binh T Nguyen

Kelly Justin McCrystle

Bodo Quint

Stevan Nielsen

Joost J Fierens

Suk-Woo Ha

Evelyn N Haynes

Karl-Ludwig Eckert

Per-Ola Kimblad

Sung Woo Min

Peter W Gregg

Jesus Magana

Timothy C Reynolds

Pamela A Kramer-Brown

Lorcan James Coffey

Gregory Waimong Chan

Curtis James Caton

Hugo Antonio Cobar

Wouter Erik Roorda

Eugene T Michal

John Joseph Stankus

Shubhayu Basu

William Earl Webler, Jr

Richard Roy Newhauser, Jr

Keif M Fitzgerald

Florian Ludwig

Keith R Cromack

Dan Wallace

Anthony S Andreacchi

Spencer C Noe

Boris Anukhin

John L Toner

Juan F Granada

Sandra E Burke

Rainer Bregulla

David A Mackiewicz

Karim Said Osman

Larry G Baughman

David S Tung

Henry Thek Chan

Austin M Leach

Rodney Charles Ow

Shengmin Mei

Jens Trötzschel

Zachary R Vidlund

Gregory Matthew Hyde

Austin Michael Sherman

Bodo Stefan Josef Quint

Martina Bremser

Neil Burkhart

Rommel Cababaro Lumauig

Daniel Tucker Wallace

Kim Lela Hayenga

Russell Patrick Shelton

Gabriel H Monteon

John Hill

Duane M DeMorre

Diana Chu

Gregory W Johnson

Z C Lin

Jürgen Wachter

Fransisco Valencia

Sean A Mcniven

A prosthetic mitral valve includes a stent frame and an anchor assembly coupled to and peripherally surrounding the stent frame. The anchor assembly includes atrial anchors on the inflow end, ventricular anchors on the outflow end, and a central waist portion disposed therebetween. The anchor assembly generally defines an hourglass shape wherein the atrial and ventricular anchors flare radially outward and the central waist portion has a relatively smaller diameter. The prosthetic valve may include a gasket disposed peripherally around the central waist portion to seal the space between the body of the valve and the native valve annulus to prevent paravalvular leakage without increasing the profile of the valve to allow for smooth insertion into and deployment from a delivery device. The prosthetic valve may alternatively include a sealing fabric surrounding the anchor assembly defining a radial protrusion around the central waist portion to seal the native annulus.

Collapsible gasket seal for heart valve

An intravascular device delivery system includes an elongated member with a distal end cap and a delivery disc that are longitudinally movable using a disc handle. A main body of the disc handle is configured to move the distal end cap and a movable body of the disc handle is configured to move the delivery disc. The movable body is movable relative to the main body, and the main body and movable body are movable together.

Systems and methods for loading and deploying an intravascular device

An intravascular device delivery system has an elongated member with a flexible hypotube. The hypotube can be rotationally keyed to a steerable catheter. The flexible hypotube includes one or more cuts to allow bending of the flexible hypotube within a first plane. The steerable catheter is steerable to bend the flexible hypotube within the first plane, and longitudinally movable relative to the flexible hypotube to allow distal movement of the steerable catheter relative to a distal end of the flexible hypotube.

Mechanical interlock for catheters

An intravascular device delivery system has an elongated member, a guidewire receiving member, and a distal cap longitudinally fixed to a guidewire receiving member. The distal cap includes an insert having an elongate member, a rim member radially separated from the elongate member, and a wall member supporting the rim member, the wall member being disposed between the rim member and the elongate member.

Insert for distal end cap

The present disclosure describes devices, systems, and methods for intravascularly delivering an implantable device to a targeted anatomical site such as the mitral annulus. A delivery system includes a delivery member coupled to a handle assembly and extending distally from the handle assembly. A delivery catheter is concentrically positioned within an outer member and configured to advance the intravascular device relative to the outer member. The delivery catheter includes a distal can structure configured to house at least a portion of the intravascular device in a compressed, pre-deployed position.

Delivery system for heart valve replacement

A steerable catheter has a body with an outer surface and an inner surface defining a central lumen. The outer surface and inner surface define a wall of the body, which has a plurality of steering lumen and control lumen extending longitudinally therethrough. The body includes a body material. The steering lumen and control lumen have a control lumen lining and steering lumen lining, respectively, with a higher durometer than the body material. A steering wire is positioned within the steering lumen and a control wire is positioned within the control lumen.

Combination steerable catheter and systems

Intravascular delivery system

The present disclosure describes devices, systems, and methods for loading, delivering, positioning, and deploying an artificial heart valve device at the mitral annulus. A delivery system includes a delivery member coupled to a handle assembly and extending distally from the handle assembly. The valve device is attached at the distal end of the delivery member, and is constrained within a valve cover of an outer sheath. A delivery catheter is configured to advance the valve relative to the outer sheath, and a suture catheter includes sutures/tethers which maintain proximal tension on the valve prior to deployment.

Systems and methods for delivering and deploying an artificial heart valve within the mitral annulus

A method for sealing and flushing a delivery member includes sealing one or more lumens and flushing air from the one or more lumens. An interventional device delivery system includes a handle assembly and a delivery member. The handle assembly includes a catheter holder with a passageway therethrough. A flush block is associated with the catheter holder and has a flush port and a flush chamber. The delivery member is associated with the handle assembly and includes a plurality of catheters. At least one of the catheters has a proximal end disposed within the passageway in the catheter holder and is in fluid communication with the flush chamber.

Methods, systems, and devices for sealing and flusing a delivery system

A delivery guidewire for navigating a catheter in the heart to deliver a valve prosthesis. The delivery guidewire comprising an elongated core, an outer sleeve disposed on the elongated core, and a coil disposed on a distal portion of the elongated core. The delivery guidewire having a first section having a generally uniform diameter and a second section having a tapering section. A distal portion of the second section of the delivery guidewire comprises a pigtail shape atraumatic tip which can remain in the left ventricle.

Delivery guidewire

An intravascular device delivery system includes a distal end cap to connect an elongated member of the intravascular device delivery system to an intravascular device. The distal end cap includes at least one connection member radially movable relative to the distal end cap that is configured to engage with a complimentary recess in the intravascular device.

Delivery catheter distal cap

An intravascular delivery system includes a delivery sheath capable of transmitting a predetermined tension or compression force in a longitudinal direction while maintaining flexibility to navigate tortuous anatomy. A method of delivering a medical device includes inserting an intravascular device delivery system including a delivery sheath having a continuous spine into a bodily lumen. A distal longitudinal force is applied to the delivery sheath. The distal force is transmitted through the continuous spine and across one or more slit cuts of the delivery sheath. A proximal longitudinal force is applied to the delivery sheath. The proximal longitudinal force is transmitted through the continuous spine of the delivery sheath.

Intravascular device delivery sheath

The present disclosure describes devices, systems, and methods for intravascularly delivering an implantable device at the mitral annulus. A delivery system includes a delivery member coupled to a handle assembly and extending distally from the handle assembly. The intravascular device is attached at the distal end of the delivery member, and is housed within a distal piece of an outer sheath. A steering catheter is nested within the outer sheath to bend the delivery member into position. A delivery catheter is configured to advance the intravascular device relative to the outer sheath, and a suture catheter includes sutures/tethers which may be coupled to the intravascular device prior to deployment.

Systems and methods for delivering an intravascular device to the mitral annulus

A loading device configured to radially collapse an expandable medical implant may include an operating handle having an opening therein extending along a longitudinal axis, a native sheath coupled to the operating handle and partially extending into the opening, such that the native sheath is configured to translate relative to the operating handle parallel to the longitudinal axis, a removable sheath removably coupled to the native sheath, an actuation rod extending parallel to the longitudinal axis at least partially through the opening, a lumen of the native sheath, and a lumen of the removable sheath, a distal end of the actuation rod being configured to be removably coupled to the expandable medical implant, and a first control element movable relative to the operating handle and coupled to the native sheath, the first control element being configured to translate the native sheath and the removable sheath relative to the operating handle.

Cardiac valve loading devices and systems

Growing community of inventors

Aptos, CA, United States of America

Randolf Von Oepen