University of Virginia Patent Foundation

University of Iowa Research Foundation

Angeion Corporation

Other

University of Minnesota

Heraeus Medical Components LLC

Phraxis, Inc.

Randall S Nelson

Steven E Scott

Mark W Kroll

George T Gillies

Matthew A Howard

Marcel Utz

Timothy Brennan

Robert Shurig

Brian Dalm

Stephen Kenneth Sundquist

Theodore P Adams

Roger W Dahl

Robert J Ziebol

Charles Loeb Truwit

Dennis A Brumwell

Joseph S Perttu

Alexander S Yevzlin

Paul McSherry

Malcolm Drysdale

This invention provides an device for electrical stimulation of the spinal cord. The device has an electrode assembly with a sufficiently thin profile to be implanted between the pial surface of the spinal cord and the dura mater, and secured to the dura. Electrodes on the electrode assembly are directed towards the surface of the spinal cord, and connected through the dura to a signal generator located outside the dura. Following implantation, the subject is treated by transmitting electrical signals from the signal generator through the leads to the electrodes, stimulating the subject's spinal cord.

Medical device that applies electrical stimulation to the spinal cord from inside the dura for treating back pain and other conditions

One aspect is a medical lead interconnect system. The medical lead interconnect system is configured to selectively electrically couple a linear array of contact rings of an implantable medical lead to an electrical outlet coupling. The medical lead interconnect system includes a housing with an electrical outlet, a pair of plates position within the housing and has a plurality of connector pins, a biasing member configured bias the pair of plates toward one another, and a cam configured to rotate between an open position in which the pair of plates are biased towards one another, and a closed position in which the pair plates are forced apart.

Implantable lead interconnect system having a rotating cam

A method for treating intractable pain via electrical stimulation of the spinal cord. Remote, non-contact stimulation of a selected region of spinal cord is achieved by placement of a transceiver patch directly on the surface of that region of spinal cord, with said patch optionally being inductively coupled to a transmitter patch of similar size on either the outer or inner wall of the dura surrounding that region of the spinal cord. By inductively exchanging electrical power and signals between said transmitter and transceiver patches, and by carrying out the necessary electronic and stimulus signal distribution functions on the transceiver patch, the targeted dorsal column axons can be stimulated without the unintended stray stimulation of nearby dorsal rootlets. Novel configurations of a pliable surface-sheath and clamp or dentate ligament attachment features which realize undamaging attachment of the patch to the spinal cord are described.

Implanting an electrode array against the spinal cord inside the dura for stimulating the spinal cord and treating pain

Electrode array device configured for placement inside the dura for direct spinal cord stimulation

An anastomotic connector comprises a generally tubular access port having a first end and a second end and a main body portion in fluid communication with the second end of the access port that is structured to be deployed within a fluid passageway. The main body portion includes an expandable mesh frame defining a pair of flanges extending outwardly from the second end of the access port and a retention strap extending across the second end of the access port. The pair of flanges and the retention strap are structured to exert a radial force on an internal surface of a fluid passageway when the mesh frame of the main body portion is expanded within the fluid passageway. Furthermore, the pair of flanges and the retention strap allow the passage of fluid to the distal tissues that the native fluid passageway is supplying.

Anastomotic connector

There is disclosed method and apparatus for retaining a reservoir for a therapeutic agent between the scalp and cranium of a subject, including providing a deformable pouch or rigid cylinder for dispensing the therapeutic agent from the reservoir to a location in the body of the subject. In one embodiment, a pump is used to pump the agent from the reservoir to the location in the subject's body. In another example embodiment, there is provided method and apparatus for forming at least one cavity in the cranium of the subject, and placing at least a portion of the pump in the cavity. Power is applied to the pump in a variety of ways.

Implantable reservoir and system for delivery of a therapeutic agent

An intraoperative defibrillation test system for establishing defibrillation thresholds for an implantable cardioverter defibrillator (ICD) uses the actual ICD housing electrode, rather than a test housing electrode, as part of the test system. The intraoperative defibrillation test system includes the ICD, an external test station, and a test cable interconnecting the ICD with the test station. In one embodiment, the test cable is only connected to the ICD housing electrode and other test cables are used to connect to other implanted electrodes. In another embodiment, the test cable includes multiple conductors for connecting to all of the electrodes associated with the ICD, including the ICD housing electrode. In a further embodiment, the test cable includes a distal connector block that serves as a three-way T-between at least one port in a header of the ICD and an electrode lead.

Defibrillation test system using actual ICD housing electrode

An implantable cardioverter defibrillator capable of subcutaneous positioning within a patient delivers at least one electrical cardioversion/defibrillation countershocks to the heart of the patient. The implantable cardioverter defibrillator includes a housing, circuitry positioned within the housing to control delivery of the countershocks, and an energy source coupled with the circuitry to provide electrical energy to a capacitor in the circuitry that stores the electrical energy for delivery of the countershocks. Because the circuitry is susceptible to undesirable electromagnetic coupling effects of origin external to the circuitry, particularly the capacitive coupling effects between the circuitry and the housing of the device when at least a portion of the housing is utilized as an electrode, the implantable cardioverter defibrillator also includes a conductive shield, disposed between the housing and the circuitry, to shield the circuitry against such undesired coupling effects.

Shield for implantable cardioverter defibrillator

The present invention is a one piece, disposable pulse generator emulator for emulating a subcutaneous implantable cardioverter defibrillator (ICD) having an active housing electrode. The emulator of the present invention is for use with an external test system to screen a patient for candidacy for an ICD by determining the patient's minimum defibrillation threshold voltage. The one piece, disposable emulator has a housing that has substantially the same conductive geometry as the desired implantable pulse generator.

One piece disposable threshold test can electrode for use with an

A low profile defibrillation catheter is disclosed which is much thinner than existing devices. The thin structure is provided by using the current conductor coil as a first electrode coil and the same materials as the conductor for the second electrode. The second electrode coil is bonded to the second conductor coil and wound in the same direction. The thin design is motivated by an electrical field analysis which reveals that the length of the catheter is the important determinant of defibrillation efficacy, and that the large radius and surface area of prior art devices were less beneficial.

Low profile defibrillation catheter

An electrode system for an implantable cardioverter defibrillator. The electrode system includes a conductive structure which is physically and electrically connected to the housing or can of the implantable cardioverter defibrillator and is used as an electrode in combination with an existing implantable cardioverter defibrillator electrode or electrodes. The electrode system provides a therapeutically significant increase in the effective surface area of the implantable cardioverter defibrillator's electrodes without requiring an additional header connection, feedthru, or cable.

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Pine Springs, MN, United States of America

Randall S Nelson