University of Oklahoma

Randal May

Courtney W Houchen

Sripathi M Sureban

Nathaniel Weygant

Dongfeng Qu

Parthasarathy Chandrakesan

Shrikant Anant

William L Berry

Antibodies and antigen-binding fragments thereof that specifically bind to human DCLK1 protein, hybridomas or other cell lines which express such antibodies and antigen-binding fragments thereof, nucleic acids, vectors, and host cells comprising nucleic acids which encode such antibodies and antigen-binding fragments thereof, and methods of use thereof are disclosed. In at least certain non-limiting embodiments, the antibodies or antigen-binding fragments thereof specifically bind to an epitope within isoform 2 or 4 of DCLK1 protein.

Anti-doublecortin-like kinase 1 antibodies and methods of use

Monoclonal antibodies against DCLK1 and conjugates containing these monoclonal antibodies are disclosed. Methods of producing and using these monoclonal antibodies are also disclosed.

Anti-DCLK1 monoclonal antibodies and methods of production and use thereof

DCAMKL-1 has been identified as a biomarker for stem cells, as well as cancer stem cells. Methods of detecting the presence of at least one stem cell, methods of isolating stem cells, and methods of inhibiting growth of cancer cells utilizing DCAMKL-1 are disclosed herein.

SiRNA-mediated inhibition of doublecortin and Ca2+/calmodulin-dependent kinase-like-1

Growing community of inventors

Oklahoma City, OK, United States of America

Randal May