St. Jude Medical, Cardiology Division, Inc.

Caisson Interventional, LLC

Ramji T Venkatasubramanian

Todd J Mortier

Cyril J Schweich, Jr

Kavitha Ganesan

Andrew T Forsberg

Erik O Martz

Douglas J Krone

Peter Nicholas Braido

Mina Safwat Fahim

Julia Ann Schraut

Aditee Kurane

Jaishankar Kutty

John Anderson Hauck

Neelakantan Saikrishnan

Anthony David Hill

Riki Chou Thao

Ram Kumar Balachandran

Alex Alden Peterson

Peng Peng

Chad Joshua Green

Katherine A Ahmann

Eunhee Cho

Cyril J Schweich

Jr Schweich Cyril J

Jr Cyril J Schweich

Aditee A Kurane

Jaishankar K Kutty

Alex A Peterson

Prosthetic mitral valves described herein can be deployed using a transcatheter mitral valve delivery system and technique to interface and anchor in cooperation with the anatomical structures of a native mitral valve. This document describes prosthetic heart valve designs and techniques to manage blood flow through the left ventricular outflow tract. For example, this document describes prosthetic heart valve designs and techniques that reduce or prevent obstructions of the left ventricular outflow tract that may otherwise result from systolic anterior motion of an anterior leaflet of the native mitral valve.

Systems and methods for heart valve therapy

Prosthetic mitral valves described herein can be deployed using a transcatheter mitral valve delivery system and technique to interface and anchor in cooperation with the anatomical structures of a native mitral valve. This document describes prosthetic heart valve designs that interface with native mitral valve structures to create a fluid seal, thereby minimizing mitral regurgitation and paravalvular leaks. This document also describes prosthetic heart valve designs and techniques to manage blood flow through the left ventricular outflow tract. In addition, this document describes prosthetic heart valve designs and techniques that reduce the risk of interference between the prosthetic valves and chordae tendineae.

A prosthetic heart valve includes a collapsible and expandable stent having a proximal end, a distal end, an annulus section adjacent the proximal end and an aortic section adjacent the distal end. The stent is formed of a plurality of struts. A cuff is coupled to the stent. The cuff has one or more features configured to reduce abrasion and/or perivalvular leakage.

Cuff configurations for prosthetic heart valve

A system for detecting the dimensions and geometry of a native valve annulus for trans-catheter valve implantation includes a compliant balloon and a shaft within the balloon. One or more drive electrodes may be affixed to a surface of the balloon, and one or more sense electrodes may be affixed to the shaft. After insertion of the balloon into the native valve annulus, the drive electrodes may be energized with a predetermined voltage. Using a trained statistical model and the voltages measured at the sense electrodes, initial estimates of the cross-section of the valve annulus may be obtained. The initial estimates may then be provided to an optimization model of the valve annulus to obtain a highly accurate prediction of the cross-section of the valve annulus.

System and method for assessing dimensions and eccentricity of valve annulus for trans-catheter valve implantation

A prosthetic heart valve includes a collapsible and expandable stent having a proximal end, a distal end, an annulus section adjacent the proximal end and an aortic section adjacent the distal end, the stent including a plurality of struts. The heart valve further includes a collapsible and expandable valve assembly including a cuff and a plurality of leaflets, the cuff being coupled to selected ones of the plurality of struts and having microspheres disposed therein. The microspheres are capable of expanding upon contact with blood.

Systems and methods for medical interventional procedures, including approaches to valve implantation. In one aspect, the methods and systems involve a modular approach to mitral valve therapy.

Two stage anchor and mitral valve assembly

A sizing device for a collapsible prosthetic heart valve, the sizing device includes a collapsible and expandable balloon having a proximal end, a distal end. At least one microelectromechanical sensor is coupled to the balloon, the at least one sensor being capable of measuring information related to size and stiffness of tissue.

Balloon sizing device and method of positioning a prosthetic heart valve

A sizing device for a collapsible prosthetic heart valve includes a collapsible and expandable stent. A microelectromechanical sensor is coupled to the stent, the sensor being capable of collecting information related to the size and stiffness of tissue.

Sizing device and method of positioning a prosthetic heart valve

Growing community of inventors

Maple Grove, MN, United States of America

Ramji T Venkatasubramanian