City Technology Limited

Life Safety Distribution Ag

Celsis International, Plc

Ramin Pirzad

Anthony Cooke

Peter Leonard Grant

Nicholas Peter Foote

A method of determining allergen activity in dust comprises: providing a dust sample; extracting from the dust sample at least one breakdown component or proteins or peptides; reacting the extracted at least one breakdown component with a colorimetric amine detection reagent such as TNBSA; and quantitatively measuring the intensity of any resulting coloration. The allergen activity may be gauged by the intensity of coloration.

Allergen detection apparatus

Diagnostic testing apparatus for evaluating entrainable substances (e.g. for determining allergen activity in house dust), comprising a housing for collection and testing of entrainable substances, the housing having: an inlet; an outlet; a filter disposed between the inlet and the outlet which is configured to capture substances entrained in air flowing from the inlet to the outlet; a reservoir for storing fluid for use in evaluating substances captured on the filter; and means for releasing stored fluid from the reservoir onto the filter.

Assay device for evaluating entrainable substances

Allergen detection

An assay device comprises a tube, a removable top part and a bottom part, wherein an elongate member with a swab at its distal end is mounted on the top part, the top part includes a compartment containing liquid and partly defined by a first frangible membrane that can be ruptured to release the liquid into the tube, and the bottom part contains a reagent and is partly defined by a second frangible membrane that can be ruptured on movement of the bottom part relative to the tube. Reaction occurring in the bottom part can be observed through a window. This reaction may be of the type involving amplification of say, ATP, e.g. by providing AMP, glucose-6-phosphate (G6P), adenylate kinase, glucokinase and reagents that convert glucose (G) to give a color, whereby the following reactions occur

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St. Ives, United Kingdom

Ramin Pirzad