The Administrators of the Tulane Educational Fund

Other

Ramesh Ayyala

Vijay Thomas John

Diane Blake

Vijay T John

Krzystof Reiss

Diane A Blake

Krzysztof Reiss

Thiruselvam Ponnusamy

The disclosure provides drug delivery devices and methods of making and using the drug delivery devices. The devices include single and multi-layer polymer films made by a breath figure technique having therapeutic agents associated therewith. For example, the devices may be a dual layer polymer film wherein the first layer includes a therapeutic agent incorporated into it by spin coating the first agent with a polymer solution and the second agent is incorporated into the second layer by loading the agent into pores of the second layer after it is spin coated onto the first layer. In some cases one layer provides a burst release and the second layer provides a slow release drug delivery profile. The devices may take on the form of a surgical mesh with a slow release therapeutic drug.

Drug delivery devices and methods of making and using same

An ophthalmological device comprises an implant member carrying an antifibrotic agent that is released slowly over a prolonged period when inserted into a wound in an eye produced by surgery. The member is placed in the vicinity of a wound created during the surgery to inhibit inflammatory cell proliferation, thereby preventing the growth of fibrous tissue after the eye surgery.

Device for delivery of antifibrotic agents and method

Growing community of inventors

New Orleans, LA, United States of America

Ramesh Ayyala