Other

Ramamohan Rao Davuluri

Ravi Ponnaiah

Guruswamy Batthini

Praveen Kumar Neela

Sanjay Kumar Dehury

Naresh Dongari

Selvaraju K

Nandkumar Mecherili Valsan

Dhanunjaya Naidu

Prasad Chlnv

Telagareddy Venkata Narasimharao

Kosireddy Ravanababu

Santhosh Dummu

Ravi Kanth Sribhashyam

Deepthi Vpss

Swetha Mustyala

Kallepally Sudheer

Guruswamy Batthni

Sudheer Kallepalli

Chandra Murthy V R Medida

The invention is a novel process for the preparation of lacosamide by employing novel intermediates of formula III and IV: 

Process for the preparation of (R)-N-benzyl-2-acetamido-3-methoxypropionamide

A novel process for the preparation of 6-perdeoxy-6-per-halo Gamma cyclodextrin which is a useful intermediate in the synthesis of Sugammadex is disclosed in the invention. The process involves reacting Gamma cyclodextrin with phosphorous halide in the presence of organic solvent.

Process for preparation of Sugammadex

An improved process for the synthesis of 3-[2-[4-((6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]-pyrimidin-4-one (Paliperidone) and Paliperidone Palmitate through a novel intermediate (2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-9-hydroxy-4H-pyrido [1,2-a]pyrimidine-4-one Palmitate ester.

Preparation of 3-[2-[4-((6-fluoro-1, 2-benzisoxazol-3-yl)-l-piperidinyl)-6, 7, 8, 9-tetrahydor-9-hydroxy-2-methyl-4H-pyrido[ 1, 2-A]-pyrimidin-4-one(paliperidone) and paliperidone palmitate

The invention provides a novel process for the synthesis of 2-(2-hydroxyphenyl)-benz[1,3]oxazin-4-one, the process comprising of reacting the salicylic acid with salicylamide in the presence of p-toluenesulfonyl chloride, base and solvent. The use of 2-(2-hydroxyphenyl)-benz[1,3]oxazin-4-one in the preparation of Deferasirox is also disclosed in the invention.

Process for the preparation, of 2-(2-hydroxyphenyl)-benz [1, 3] oxazin-4-one and its use for preparation of 4-[3, 5-bis (2-hydroxyphenyl)-IH-I, 2, 4-triazolTI-yl] benzoic acid

The invention relates to a novel, industrially viable, cost effective process for the preparation of 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxamide commonly known as Rufinamide and intermediates thereof.

Process for preparation of rufinamide

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San Clemente, CA, United States of America

Ramamohan Rao Davuluri