Neuroderm, Ltd.

Ram Nadler

Nir Lilach

Yoav Tikochinsky

Tamir Ben David

Dmitry Golom

Serdar Ozsumer

Tsabar Mor

Rami Grossfeld

Eran Shor

Daniel Shaki

Shai Alfandari

An improved device delivers a fluid medicament to the subcutaneous tissue of a user. The device is better suited for patients with Parkinson's Disease and other central nervous system disorders, than conventional infusion devices. The device can include a reusable part including a drive component (e.g., motor) and control electronics and a disposable part including a medicament reservoir. Medicament can be evacuated from the medicament reservoir by a plunger assembly that includes a plunger attached to a lead screw that is rotated by a nut, all within the disposable part. The device can be fluidically coupled with the tissue via a flexible cannula. Various embodiments relate to an improved cannula insertion mechanism that delivers the cannula under a force applied by a spring. Various embodiments relate to improved filling of the device, for example, using a vial adapter and an automated filling station.

Device for subcutaneous delivery of fluid medicament

The application is directed to a vial adapter for attaching a medicament vial to a medicament delivery device having a reservoir adapted to receive and contain the medicament. The vial adapter can include a housing with two ports (one for attaching the reservoir and the other for attaching to the vial), a hollow needle that pierces septums sealing each of the reservoir and the vial, and a floating part that fixedly holds the hollow needle. Clearance between the floating part and the housing can enable relative movement of the floating part.

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Haifa, Israel

Ram Nadler