St. Jude Medical, Cardiology Division, Inc.

Covidien LP

St Jude Medical, Atrial Fibrillation Division, Inc

Boston Scientific Scimed, Inc.

Ram Kumar Balachandran

D Curtis Deno

John Anderson Hauck

Neelakantan Saikrishnan

Anthony David Hill

Jeffrey H Vogel

Riki Chou Thao

Paul Noffke

Stéphane Massé

John Anders Bostrom

Ramji T Venkatasubramanian

Thomas Andrew Albrecht

Troy Terrance Tegg

Dale Eric Just

Braden Eliason

Stéphane MassÉ

Braden J Eliason

A system for determining electrophysiological data comprising an electronic control unit configured to acquire electrophysiology signals from a plurality of electrodes () of one or more catheters, select at least one clique of electrodes from the plurality of electrodes () to determine a plurality of local E field data points, determine the location and orientation of the plurality of electrodes, process the electrophysiology signals from the at least one clique from a full set of bipole subcliques to derive the local E field data points associated with the at least one clique of electrodes, derive at least one orientation independent signal from the at least one clique of electrodes () from the information content corresponding to weighted parts of electrogram signals, and display or output catheter orientation independent electrophysiologic information to a user or process.

System and method for local electrophysiological characterization of cardiac substrate using multi-electrode catheter

Electrode assemblies include segmented electrodes disposed on a catheter. The segmented electrodes can be constructed at the tip of the catheter or more proximally located. Tip electrodes can be constructed from an electrically-insulative substrate covered with a conductive material. The conductive material can be deposited on the electrically-insulative substrate to form a single tip electrode or multiple segmented electrodes. In some embodiments the tip electrode can include irrigation flow holes for irrigation. A method of manufacturing a tip electrode comprising a thin layer of conductive material deposited on an electrically-insulative substrate is disclosed. Segmented ring electrodes can be constructed from segmented ring electrodes that can be equally separated around a circumference of a catheter. The segmented ring electrodes can be formed into segmented electrode subassemblies that can then be joined to a catheter shaft.

Ablation catheter designs and methods with enhanced diagnostic capabilities

A system and method for obtaining an OIS coordinate frame comprising an electronic control unit configured to determine a local 3D electric field loop, create a zero mean version of E(t) over a depolarization interval, compute an &#x116; value at each of a plurality of time intervals, compute an initial estimate of &#x175; from a cross product of E and the &#x116; value for each of the plurality of time intervals, average the initial estimate of &#x175; from each of the plurality of time for a best estimate of &#x175;, determine a plurality of &#xe2;(&#x3b8;) values and using the corresponding {circumflex over (n)}(&#x3b8;) values, compute a composite match score, and choose at least one best value for &#xe2; and a best value for {circumflex over (n)}.

Systems and methods for orientation independent sensing

Described are surgical implants that include releasable reinforcement, and related methods, particular example implants and methods being useful for treating pelvic tissue, cardiac tissue, and hernia, wherein the releasable reinforcement can be released (removed or disabled) during a surgical procedure to affect a mechanical property of the implant or a portion of the implant.

Implants and methods for treatments of pelvic conditions

The present invention relates to surgical implants with adjustable size features, and methods for treating pelvic conditions by use of the implants.

A stent comprising a stent body and a plurality of cells is disclosed. The stent body defines a length. Each cell includes two structural members extending in an undulating pattern. Each structural member includes a plurality of cell segments defining a plurality of nodes therebetween. At least one node includes a non-constant radius of curvature.

Stent

A system for determining the dimensions of a native valve annulus may include a sensing catheter, a transmitter, and a computing device. The sensing catheter may include a shaft extending in a longitudinal direction; a plurality of splines attached to the shaft, the splines having an expanded condition spaced radially outward from the shaft; and at least one sensing coil located on each of the splines. The transmitter may generate a magnetic field to induce a potential in each of the sensing coils, and the computing device may identify the positions of the sensing coils based on the induced potentials.

System and method for intraprocedural assessment of geometry and compliance of valve annulus for trans-catheter valve implantation

A system for detecting the dimensions and geometry of a native valve annulus for trans-catheter valve implantation includes a compliant balloon and a shaft within the balloon. One or more drive electrodes may be affixed to a surface of the balloon, and one or more sense electrodes may be affixed to the shaft. After insertion of the balloon into the native valve annulus, the drive electrodes may be energized with a predetermined voltage. Using a trained statistical model and the voltages measured at the sense electrodes, initial estimates of the cross-section of the valve annulus may be obtained. The initial estimates may then be provided to an optimization model of the valve annulus to obtain a highly accurate prediction of the cross-section of the valve annulus.

System and method for assessing dimensions and eccentricity of valve annulus for trans-catheter valve implantation

A system and method are provided for determining electrophysiological data. The system comprises an electronic control unit that is configured to receive electrical signals from a set of electrodes, receive position and orientation data for the set of electrodes from a mapping system, compensate for position and orientation artifacts of the set of electrodes, compose cliques of a subset of neighboring electrodes in the set of electrodes, determine catheter orientation independent information of a target tissue, and output the orientation independent information to a display. The method comprising receiving electrogram data for a set of electrodes (), compensating for artifacts in sensor positions in the mapping system (), resolving the bipolar signals into a 3D vector electrogram in the mapping system coordinates (), manipulating observed unipolar voltage signals and the tangent component of the e-field to estimate the conduction velocity vector (), and outputting the catheter orientation independent information ().

Utilization of electrode spatial arrangements for characterizing cardiac conduction conditions

System and method for local electrophysiological characterization of cardiac substrate using multi-electrode catheters

A method for determining electrophysiology properties of tissue comprising acquiring electrical signal data from a plurality of electrodes () of one or more catheters, determining at least one electrode clique from the plurality of adjacent electrodes (), computing local conduction velocity vectors for the at least one electrode clique (), determining at least one catheter orientation independent indicator from which to classify an arrhythmia source based on one or more of an angular dependence parameter associated with a flow field of the local velocity conduction vectors, an eccentricity parameter reflecting the uniformity of local conduction velocity, and divergence and curl-like sums or closed path integral parameters associated with the local velocity vectors, and displaying a rhythm classification responsive to catheter movement thereby facilitating identification of types and causes of arrhythmia disorders.

Growing community of inventors

Maple Grove, MN, United States of America

Ram Kumar Balachandran