Chevron Research Company

Gulf Oil Corporation

Ralph P Neighbors

Loren W Hedrich

Joseph R Riden

The method which comprises administering to a tumor-containing animal derivatives of tricyclodecene-3,4,7,8-tetracarboxylic acid derivatives, preferably a compound having the following structural formula: ##STR1## or a pharmaceutically acceptable salt thereof.

Use of tricyclodecene-3,4,7,8-tetracarboxylic acid derivatives as

New N-carbamylindolines which are useful in combating unwanted vegetation by both pre-emergent and post-emergent application are compounds having the structural formula ##STR1## in which R and R.sup.3 are hydrogen or methyl, R.sup.1 is hydrogen or N,N-dimethylsulfamyl, N,N-diethylsulfamyl, N-methoxy-N-methyl-sulfamyl, bromo or chloro, X is hydrogen or fluoro and R.sup.2 is hydrogen or dimethylsulfamyl, with the provision that at least one and no more than two substituents represented by R.sup.1, R.sup.2, and R.sup.3 and X are present.

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Olathe, KS, United States of America

Ralph P Neighbors