Luminex Corporation

Rules-based Medicine, Inc.

Ralph L McDade

Ewald Alois Terpetschnig

Leonid Davidovych Patsenker

Ananda G Lugade

Kurt D Hoffacker

Karri Lynn Michael-Ballard

Adam J Jenkins

Veronica D Thomason

Michael D Spain

James P Mapes

Dominic Eisinger

Karri L Ballard

Samuel T Labrie

Methods and devices for diagnosing, monitoring, or determining obstructive uropathy or an associated disorder in a mammal are described. In particular, methods and devices for diagnosing, monitoring, or determining obstructive uropathy or an associated disorder using measured concentrations of a combination of three or more analytes in a test sample taken from the mammal are described.

Methods and devices for detecting obstructive uropathy and associated disorders

The present invention relates to improved covalent coupling of two or more entities such as biomolecules, polymer compositions, organic/inorganic molecules/materials, and the like, including their combinations, through one or more novel reactive groups attached to linker groups of 2-1000 atoms length. The present invention also contemplates the use of bifunctional bridge molecules to link two or more entities, wherein the functional groups of the bridge molecules are the novel reactive groups of the present invention.

Functionalized compositions for improved immobilization

The present invention relates to improved covalent coupling of two or more entities such as biomolecules, polymer compositions, organic/inorganic molecules/materials, and the like, including their combinations, through one or more novel reactive groups attached to linker groups of 2&#x2013;1000 atoms length. The present invention also contemplates the use of bifunctional bridge molecules to link two or more entities, wherein the functional groups of the bridge molecules are the novel reactive groups of the present invention.

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Austin, TX, United States of America

Ralph L McDade