St. Jude Medical, Cardiology Division, Inc.

St. Jude Medical, Inc.

Medtronic, Inc.

St. Jude Medical Coordination Center Bvba

Ralph Joseph Thomas

Huisun Wang

Valerie J Glazier

Khoi A Le

Bradley Charles Knippel

Jacob John Daly

Gregory R Furnish

Benjamin E Morris

Eric E Bielefeld

Gary W Geiger

Yousef F Alkhatib

Brett Allen Hillukka

Peter Nicholas Braido

Kenneth C Gardeski

Mina Safwat Fahim

Aaron J Chalekian

Kent J Smith

Daniel J Klima

Melinda Kaye Kovach

Steven Frederick Anderl

Michael R Leners

Scott Patrick Thome

Timothy John McGill

Brian James Edquist

Matt Quest

Jesse T Torbert

James F Kelley

Julia Ann Schraut

Thomas M Benson

Sounthara Khouengboua

Julia Ann Neuman

Peter J Ness

Thomas Alan Savard

Linda L Lach

Charles L Byrd

John A Matejka

Thomas Mark Benson

Valeri J Glazier

A delivery device for an implantable medical device having a retention member at an end thereof may include a shaft extending in a longitudinal direction and defining a longitudinal axis, an elongated sheath surrounding a longitudinal portion of the shaft, a compartment defined inside the sheath and adapted to receive the medical device in an assembled condition, a retainer positioned at one end of the compartment, and an energy storage element positioned on the longitudinal portion of the shaft and configured to be radially compressed by the medical device when the elongated sheath covers the compartment containing the medical device. The sheath may be slidable relative to the shaft in the longitudinal direction. The retainer may include a recess adapted to receive the retention member of the medical device in the assembled condition.

System to assist in the release of a collapsible stent from a delivery device

A delivery device for a collapsible heart valve includes an operating handle and a catheter assembly. The operating handle includes a frame defining a movement space therein, a carriage assembly moveable in a longitudinal direction within the movement space, and a coupler having locked and unlocked conditions, the coupler being operatively connected to the carriage assembly for movement therewith. The catheter assembly includes a shaft around which a valve-receiving compartment is defined, the shaft being operatively connected to one of the frame or the carriage assembly, and a distal sheath operatively connected to the carriage assembly for movement therewith between a closed condition adapted to maintain the valve in the compartment and an open condition adapted to fully deploy the valve.

Staged deployment devices and methods for transcatheter heart valve delivery

A prosthetic heart valve may include a collapsible and expandable stent having a proximal end, a distal end, an annulus section adjacent the proximal end, and a plurality of cells connected to one another in annular rows around the stent, a cuff attached to the stent, and a sealing member attached to the cuff and extending from a proximal end of the cuff to a free edge. The sealing member may be movable between an extended condition in which the free edge is located proximally of the proximal end of the stent, and an inverted condition in which the free edge is located distally of the proximal end of the stent and a first surface of the sealing member confronts an outward-facing surface of the cuff. Various mechanisms for moving the sealing member are also described.

Paravalvular sealing via extended cuff mechanisms

A delivery device for a collapsible prosthetic heart valve includes an operating handle and a catheter assembly. The operating handle may include a housing defining a movement space therein, a carriage assembly moveable in a longitudinal direction within the movement space, a deployment actuator coupled to the housing and rotatable relative to the housing, and a coupling assembly rotationally fixed to the deployment actuator. The catheter assembly may include a first shaft around which a compartment is defined and a distal sheath operatively connected to the carriage assembly. Movement of the carriage assembly in the longitudinal direction in the movement space may move the distal sheath between the closed condition and the open condition. The coupling assembly may have an engaged position in which rotation of the deployment actuator moves the carriage assembly, and a disengaged position in which rotation of the deployment actuator does not move the carriage assembly.

Devices and methods for transcatheter heart valve delivery

A delivery device may generally include a support member, a distal sheath, an outer shaft and a straightening member. The support member is adapted to hold a prosthetic heart valve. The distal sheath is slidable relative to the support member between a first position in which the distal sheath is adapted to maintain the prosthetic heart valve in a collapsed condition, and a second position in which the distal sheath is adapted to expose the prosthetic heart valve. The outer shaft is connected to the distal sheath and has a curved portion. The straightening member is slidable on the outer shaft between a proximal position in which the straightening member does not cover the curved portion of the outer shaft, and a distal position in which the straightening member covers and substantially straightens at least a portion of the curved portion of the outer shaft.

Delivery device having a curved shaft and a straightening member for transcatheter aortic valve implantation

Staged development devices and methods for transcatheter heart valve delivery

A delivery device () for a collapsible prosthetic heart valve may include an operating handle () having a housing () and a carriage selectively () fixed or movable relative to the housing, and a catheter assembly (). The catheter assembly may have an inner shaft () around which a compartment () is defined, an outer shaft () surrounding at least a portion of the inner shaft, a distal sheath () fixedly connected to the outer shaft, and a mechanism configured to apply a distal force to the outer shaft while the carriage () is fixed relative to the housing () to stretch the outer shaft from a compressed length to an extended length. The extended length may be greater than the compressed length along an axis of elongation of the outer shaft ().

Atraumatic interface in an implant delivery device

A delivery device for a collapsible prosthetic heart valve includes an inner shaft having a proximal end and a distal end, an outer shaft disposed around the inner shaft and longitudinally moveable relative to the inner shaft, and a distal sheath disposed about a portion of the inner shaft and forming a compartment with the inner shaft, the compartment being adapted to receive the prosthetic heart valve. At least one of the outer shaft or the distal sheath may have a pattern of cutouts formed therein, the pattern including at least one ring around a circumference of the at least one of the outer shaft or the distal sheath, the at least one ring having at least one of the cutouts.

Flexible catheters and methods of forming same

A delivery device for a collapsible heart valve includes an operating handle, including a frame defining a movement space therein, a carriage assembly moveable within the movement space, and a first resheathing lock having a locked position and an unlocked position. The delivery device further includes a catheter assembly, including a first shaft around which a valve-receiving compartment is defined, the first shaft being fixedly connected to one of the frame or the carriage assembly, and a distal sheath operatively connected to the carriage assembly. The distal sheath is moveable between a closed condition adapted to maintain the valve in the compartment and an open condition adapted to fully deploy the valve. With the resheathing lock in the locked position, the distal sheath is unable to move to the open condition to fully deploy the valve.

Staged deployment devices and methods for transcatheter heart valve delivery systems

A delivery system for delivering a collapsible prosthetic heart valve includes a valve support structure for supporting a collapsible prosthetic heart valve, and a distal sheath movable in a longitudinal direction relative to the valve support structure between a first position in which the distal sheath is adapted to surround a collapsible prosthetic heart valve supported on the valve support structure, and a second position in which the distal sheath is adapted to expose the collapsible prosthetic heart valve for deployment. The distal sheath is at least partially formed of an inner polymer layer, an outer polymer layer, and a tubular supporting member sandwiched between the inner polymer layer and the outer polymer layer.

Delivery system for collapsible heart valve

A prosthetic heart valvemay include a collapsible and expandable stenthaving a proximal end, a distal end, an annulus section adjacent the proximal end, and a plurality of cells connected to one another in annular rows around the stent, a cuffattached to the stent, and a sealing memberattached to the cuff and extending from a proximal endof the cuff to a free edge. The sealing membermay be movable between an extended condition in which the free edgeis located proximally of the proximal endof the stent, and an inverted condition in which the free edge is located distally of the proximal end of the stent and a first surfaceof the sealing member confronts an outward-facing surface of the cuff. Various mechanisms for moving the sealing memberare also described.

A delivery device () for an implantable medical device includes an inner shaft () extending in a longitudinal direction and defining a compartment () adapted to receive the medical device in an assembled condition, an outer shaft () surrounding a longitudinal portion of the inner shaft, and a distal sheath () operatively attached to the outer shaft (). The distal sheath () is slidable between a first position enclosing the compartment () and a second position exposing the compartment () for deployment of the medical device. A sleevesurrounds at least a longitudinal portion of the outer shaft () and provides a substantially blood tight bearing surface that facilitates sliding movement of the delivery device () in an introducer ().

Sleeve for facilitating movement of a transfemoral catheter

A transcatheter valve delivery system includes a longitudinal member extending between a proximal end and a distal end, and having a compartment adjacent the distal end for holding a medical device in a collapsed condition. An alignment element is connected to the longitudinal member and is movable relative to the longitudinal member between a stowed position and a deployed position. In the deployed position, the alignment element is configured to urge against an anatomical surface to position the longitudinal member at a desired location relative to the anatomical surface.

Alignment of an implantable medical device

Growing community of inventors

Champlin, MN, United States of America

Ralph Joseph Thomas