Mast Biosurgery Ag

Other

Medtronic Ps Medical, Inc.

Macropore, Inc.

Medtronic, Inc.

Macropore Biosurgery, Inc.

Ralph Holmes

Christopher J Calhoun

Steven R Cohen

Horst Fichtner

J Peter Amis

Kenneth K Kleinhenz

G Bryan Cornwall

Stefan M Lemperle

A method for early stabilizing of distracted connective tissue. A distraction site is at least partially covered with biodegradable, bioerodible or bioresorbable materials before a distraction procedure takes place. Distraction is performed on a connective tissue at the distraction site. The distracted connective tissue is stabilized using the biodegradable, bioerodible or bioresorbable materials.

Completely resorbable connective tissue distraction devices and techniques

A device for early stabilizing of distracted tissue that includes a first implant, a second implant, a sliding expansion mechanism and a stabilizer. The first implant is capable of being attached to a first tissue region. The second implant is capable of being attached to a second tissue region. The sliding expansion mechanism engages the first implant and the second implant for distracting the first implant away from the second implant to create a distraction space for formation of the distracted tissue. The stabilizer rigidly fixes the first implant and the second implant after disengagement of the sliding expansion mechanism to rigidly stabilize the distracted tissue. The stabilizer includes in whole or in part a biodegradable, bioerodible or bioresorbable material.

Resorbable lactide polymer thin membranes are disclosed. The thin membranes are constructed of polylactide resorbable polymers, which are engineered to be absorbed into the body relatively slowly over time in order to reduce potential negative side effects. The membranes are formed to have very thin thicknesses, for example, thicknesses between about 0.010 mm and about 0.30 mm. The membranes can be extruded from polylactide polymers having a relatively high viscosity property, can be preshaped with relatively thick portions, and can be stored in sterile packages.

Resorbable thin membranes

One aspect of the present invention is a connective tissue distraction device comprising: a first transmitting structure for transmitting force to a first tissue region and a second transmitting structure for transmitting force to a second tissue region by contact with bone, and an expansion device for exerting force distracting the first transmitting structure from the second transmitting structure. At least one of the first transmitting device, the second transmitting device and the expansion structure comprises in whole or in part a biodegradable, bioerodible or bioresorbable material.

An anti-adhesion membrane is placed onto an implant introduced into a surgical site of a patient to prevent post-surgical adhesions between the implant and surrounding tissue. The implant may comprise either biological material, such as a transplanted organ, or non-biological material such as a medical device. The membrane may be applied in a variety of ways. In one example, a membrane according to the present invention is shrink-wrapped around a pace-maker. In another example, a breast implant is spray-coated or dipped with the membrane material.

Apparatus and method for preventing adhesions between an implant and surrounding tissues

Resorbable lactide polymer thin membranes are disclosed. The thin membranes are constructed of polylactide resorbable polymers, which are engineered to be absorbed into the body relatively slowly over time in order to reduce potential negative side effects. The membranes are formed to have very thin thicknesses, for example, thicknesses between about 0.010 mm and about 0.300 mm. The membranes can be extruded from polylactide polymers having a relatively high viscosity property, can be preshaped with relatively thick portions, and can be stored in sterile packages.

Partially resorbable connective tissue distraction devices and techniques

An anti-adhesion membrane is placed onto an implant introduced into a surgical site of a patient to prevent post-surgical adhesions between the implant and surrounding tissue. The implant may comprise either biological material, whcu as a transplanted organ, or non-biological material such as a medical device. The membrane may be applied in a variety of ways. In one example, a membrane according to the present invention is shrink-wrapped around a pace-maker. In another example, a breast implant is spray-coated or dipped with the membrane material.

Resorbable polylactide polymer scar tissue reduction barrier membranes and methods of their application are disclosed. The scar-tissue reduction barrier membranes are constructed entirely of polylactide resorbable polymers, which are engineered to be absorbed into the body relatively slowly over time in order to reduce potential negative side effects. The scar tissue reduction barrier membranes are formed to have thicknesses on the order of microns, such as, for example, thicknesses between 10 and 300 microns. The membranes are preshaped with welding flanges and stored in sterile packaging.

Resorbable barrier micro-membranes for attenuation of scar tissue during healing

An apparatus for macrophotograph comprising a camera, an electronic flash unit having a variable power output, a bracket for connecting the electronic flash unit to the camera in such manner that an angle formed between an axis passing through a lens of the camera and an axis passing through the flash unit is adjustable, and a calculator device for calculating an appropriate power setting for the flash unit. The calculator device has a first set of indicia for determining the reproduction ratio between the size of the object being photographed and the size of an image of the object on film, a first set of cooperating scales for adjusting actual film sensitivity to obtain an effective film sensitivity based on the reproduction ratio, a second set of cooperating scales correlating the effective film sensitivity with the f-stop or lens opening, and a third set of cooperating scales correlating the flash to subject distance with different power outputs of the flash unit. The second and third sets of scales are positioned on the calculator device in such manner that variation of the relationship between the scales of one of the sets automatically varies the relationship between the scales of the other of the sets. The calculator device is effective to determine appropriate power settings for both macrophotography and fill flash at close distances.

Growing community of inventors

San Diego, CA, United States of America

Ralph Holmes