Basf Se Corporation

Ralf Widmaier

Rainer Dobrawa

Eberhard Schupp

Klaus Schnell

Karl-Hermann Strube

Josef Neutzner

Marianna Pierobon

Karl Kolter

Ivette Garcia Castro

Bernhard Fussnegger

Bernd De Potzolli

Martin Meister

Ulrich Filges

Nathalie Bouillo

Reinhold Dieing

Ronald Frans-Maria Lange

Olga Pinneker

Jürgen Nieberle

Andreas Gruber

Wolfgang Bouquet

Dieter Faul

Stefan Stein

Hermann Ascherl

Michael Kerber

Peter Hössel

Kathrin Meyer-Böhm

Kathrin Meyer-Boehm

Erik Bohrer

Peter Schmidt

Norbert Gebhardt

Simone Lehnert

Harald Armbruster

Hubertus Folttmann

Manfred Kroll

Frank Höfer

Peter Mendera

Ronald Frans Maria Lange

The use of copolymers obtained by free-radical polymerization of a mixture of

Use of a copolymer in the form of a solubiliser for a poorly water-soluble compound

Use of crosslinked polyvinylpyrrolidone with an average particle size of 5-60 &#x3bc;m and a hydration capacity of greater than 7 g/g as tablet disintegrant.

Fine-particle crosslinked polyvinylpyrrolidone as tablet disintegrant

Method for stabilizing polyvinylpyrrolidones, which comprises treating the polyvinylpyrrolidones with sulfur dioxide, sulfurous acid or alkali metal sulfites and then with free-radical scavenger, and converting the solutions treated in this way into the powdered polyvinylpyrrolidones by drying.

Method for the stabilization of polyvinylpyrrolidones

Use of copolymers as solubilizers for slightly water-soluble compounds

Method of producing copolymers by free-radical polymerization of at least one water-soluble N-vinyllactam and at least one hydrophobic comonomer in an organic solvent in the presence of an initiator, where the polymerization is carried out under a gauge pressure such that evaporation of the components is avoided.

Method of producing water-soluble nonturbid copolymers of at least one water-soluble N-vinyllactam and at least one hydrophobic comonomer by polymerization under increased pressure

Aqueous solutions comprising: one or more polymeric components selected from the group consisting of homopolymers of N-vinylpyrrolidone, copolymers of N-vinylpyrrolidone, and mixtures thereof; and hydrogen peroxide; wherein the hydrogen peroxide is present in an amount of 100 to 5000 ppm; and methods of stabilizing aqueous solutions containing one or more polymeric components selected from the group consisting of homopolymers of N-vinylpyrrolidone, copolymers of N-vinylpyrrolidone, and mixtures thereof.

Stabilisation of aqueous solutions of homopolymers and copolymers of N-vinylpyrrolidones

Methods of producing vinyllactam copolymers which include: providing at least one water-soluble N-vinyllactam; providing at least one hydrophobic comonomer; and subjecting the at least one water-soluble N-vinyllactam and the at least one hydrophobic comonomer to free-radical polymerization in an organic solvent in the presence of an initiator, under a combination of process measures selected from the group consisting of A and B; wherein:

Methods of producing water-soluble, non-turbid copolymers of at least one water-soluble N-vinyllactam and at least one hydrophobic comonomer

Method of producing vinyllactam copolymers by free-radical polymerization of at least one water-soluble N-vinyllactam and at least one hydrophobic comonomer in an organic solvent in the presence of an initiator under reflux conditions, where following conversion of 90 to 99% by weight of the vinyllactam used, some of the solvent is distilled off and the polymerization is continued.

Method of producing water-soluble nonturbid copolymers of at least one water-soluble N-vinyllactam and at least one hydrophobic comonomer

Method of producing vinyllactam copolymers by free-radical polymerization of at least one water-soluble N-vinyllactam and at least one hydrophobic comonomer in an organic solvent in the presence of an initiator under reflux conditions, where the initiator is introduced into the polymerization mixture from below.

Method of producing vinyllactam copolymers by free-radical polymerization of at least one water-soluble N-vinyllactam and at least one hydrophobic comonomer in an organic solvent in the presence of an initiator under reflux conditions, where the condensate formed in the reflux is returned to the polymerization mixture from below.

Method of producing vinyllactam copolymers by free-radical polymerization of at least one water-soluble N-vinyllactam and at least one hydrophobic comonomer in an organic solvent in the presence of an initiator under reflux conditions, where N-vinyllactam is added to the reflux.

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Mannheim, Germany

Ralf Widmaier