Stratec Biomedical Ag

Ralf Griebel

Peter Bendzko

Hans Joos

The invention comprises an apparatusand a methodfor purifying biomolecules. Magnetizable particlesand a group of magnetizable pinsare used for binding biomoleculesto the magnetizable particlesusing a binding buffer, and for transferring the magnetizable particlesforming a particle-biomolecule complex. The apparatuscomprises an incubation unitthat allows for an upscaling of a maximum volume of a sample material. Furthermore the apparatuscomprises counter magnetswhich are arranged on cavities. Solutionscomprising the biomoleculesand the magnetizable particlesare disposed in the cavities. The use of counter magnetsimproves the quality of an eluate. Furthermore the invention comprises a systemand a methodfor a diagnostically purifying of biomolecules. The methodfurther comprises a controlling of method steps and a selection of substances and reagents (for example the magnetizable particles) based on information automatically collected from, for example, the samples and/or derived from used substances and reagents. The systemfulfills requirements of medical diagnostics.

Apparatus and method for the purification of biomolecules

A rod assembly for the extraction of magnetizable particles from solutions is described. The rod assembly includes at least one guide element. A rod element is insertable into the at least one guide element and moveable in a direction substantially parallel to the at least one guide element. A magnet element is moveable to a distal magnet element position; wherein the distal magnet element position is located on a distal end section of the at least one guide element; wherein the at least one guide element includes an opening at a distal end. A method for the extraction of magnetizable particles from solutions is also described, as well as a magnet element for the extraction of magnetizable particles from solutions.

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Birkenfeld, Germany

Ralf Griebel