9541659 Canada Inc.

Other

Petrovax, L.l.c.

Rakhim Musaevich Khaitov

Ravshan Ataullakhanov

Tatyana M Melnikova

Aleksey V Pichugin

Rem V Petrov

Arkady Vasilievich Nekrasov

Elena Nikolaevna Goloschapova

Nikolai Mikhailovich Goloschapov

Ljubov Elizarovna Kostjuk

Galina Ivanovna Tsyvkina

Nikolai Alexandrovich Stukalov

Elena Andreevna Michurina

Vladimir Kuzmich Grishin

Emma K Daugalieva

Tamara Petrovna Filipskikh

Ravshan I Ataullakhanov

Aleksey Vasilievich Pichugin

Ravshan Inoyatovich Ataullakhanov

Tatyana Mikhailovna Melnikova

The present disclosure relates to pharmaceutical compositions including an active substance with antimicrobial, antiviral, and immunoistimulatory activities. The disclosure further provides methods of treating bacterial or viral infections and methods of enhancing immune function using the active substance.

Pharmaceutical compositions having antibacterial, antiviral, and other immunostimulatory activities

A method of producing a substance with antimicrobial, antiviral, and immunostimulatory activities, particularly towards dendritic cells is proposed, provides for using the chopped potato sprouts as plant raw materials are extracted with water, then the aqueous extract is centrifuged, a salt agent is added, and the obtained saline solution is then concentrated using ultrafiltration through a 300-kD filter, then the solution is frozen for 24 hours, thawed, and filtered, and the pellet thus obtained is removed, and the raw peptidoglycan is precipitated from the solution by using an acidic salt agent and is further re-solubilized with alkali, then the alkaline solution is dialyzed against distilled water on a 12 kD filter, and the peptidoglycan having a molecular weight of 500 kD to 17000 kD is purified from the resulting solution using gel permeation chromatography.

Immuno-modulator exhibiting antimicrobial and anti-mycrobacterial activities, method for producing the same and pharmaceutical preparation

A compound for protecting a vertebrate against infection by helminths comprising hyaluronidase covalently coupled to an immunostimulating carrier, in preferred form, the immunostimulating carrier to which the hyaluronidase is covalently coupled comprising a copolymer of ethylenepiperazine N-oxide and N-ethylacetylethylenepiperazinium bromide (hereafter referred to as 'SYNPOL'), and a process for protecting a vertebrate against infection by helminths comprising administration to the vertebrate of a therapeutically effective amount of a compound comprising hyaluronidase covalently coupled to an immunostimulating carrier, preferably SYNPOL, in preferred form, the compound being administered to the vertebrate in the form of a vaccine.

Compounds for the prevention and treatment of helmith infections

Growing community of inventors

Moscow, Russia

Rakhim Musaevich Khaitov