Verification Technologies, Inc.

Sun Chemical Corporation

Other

Honeywell International Inc.

Companion Diagnostics Inc.

Rakesh Vig

Richard H Selinfreund

Richard P Gill

Jeffrey M Drew

Peter D Miller

Donald Roland Goyette

Michael Jablon

Ewell Cook

Anthony Saglimbeni

George Leotsakos

Wen Chiao

Scott Gerger

Henry F McInerney

Stephen Armstrong

J Christopher Philips

Russell J Schwartz

Tatiana Romanova

Cristina Najemian

Manfried Braun

Junzhong Li

Don DeRussy

Stephen Postle

Wen B Chiao

Mark Richard Wheeler

Marc Dekerf

Friedrich Behringer

Daniel F Gloster

Richard L Selinfreund

Dan Gloster

Sarka Aubrecht

Steve Postle

Fredrich Behringer

John D Clay

Mike Cunningham

Chris Phillips

Fred J Behringer

Junzhing Li

George S Leotsakos

A matte finish coating for application to a substrate includes in a mixture a coating substance and a micronized polymer matting agent. The matte finish coating comprises the micronized polymer matting agent in an amount, by overall weight of the matte finish coating, of about 0.5% to about 15%.

Coatings containing micronized polymers as matting agents

Anti-blocking compositions are disclosed that include a wax or mixture of waxes effective to reduce, retard or prevent blocking of a viscoelastic solid when applied to the surface of such a solid. Also disclosed are methods of reducing, retarding or preventing blocking of a viscoelastic solid, and the products of those methods which are viscoelastic solids resistant to blocking.

High performance anti-block treatments for viscoelastic solids

An adhesion composition comprising a) a first polymer that is selected from the group consisting of acrylic polymers, acrylonitrile butadiene, butyl rubber, cellulose acetate, cellulose butyrate, epoxy resins, ethylene vinyl acetate, natural rubber, neoprene, phenolic polymers, polyurethanes, polyvinyl acetate, polyvinyl alcohol, styrene butadiene rubber, casein, dextrin, starch, copolymers thereof and combinations thereof; b) a second polymer selected from the group consisting of ethylene-acrylic acid copolymer, oxidized polyethylene, oxidized ethylene-vinyl acetate copolymer, maleated polyolefin and combinations thereof; and c) a surfactant; where the composition is water-based, having a solids content of greater than about 30% based on the total weight of the composition, with a particle size of about 10 nm to about 2000 nm, and is adapted for adhesion to substrates; and where the first and second polymers are different. The adhesion composition can also comprise a tackifier resin selected from the group consisting of rosin ester resin, rosin acid resin, synthetic hydrocarbon resin, synthetic terpenic resin and combinations thereof. Applications of the composition are also disclosed.

High performance water-based adhesion compositions and applications

Methods for determining the efficiency of a therapeutic. In at least one embodiment of a method of determining the efficacy of a therapeutic compound, the method comprises the steps of treating a subject having a disease state with an effective amount of therapeutic compound, harvesting at least one cell from the subject following a treatment with the therapeutic compound, bringing the at least one cell into contact with a stabilizing compound capable of completely or substantially preventing the degradation or inactivation of a diagnostic marker for the disease state, analyzing the at least one stabilized cell for the at least one diagnostic marker, creating a marker profile from at least one result determined from analyzing the at least one stabilized cell, and comparing the marker profile with at least one previous marker profile to determine efficacy of the therapeutic compound on the disease state.

Methods for determining the efficiency of a therapeutic

Systems and methods of screening biomarkers in bodily fluids. According to at least one embodiment of the system for analyzing stabilizing agents of the present disclosure, the system comprises a detection platform comprising a plurality of detection sites each capable of receiving a diagnostic marker, a stabilization agent, and a detection agent. The system, in at least one embodiment, further comprises a detection device capable of determining a binding characteristic between the detection agent and the diagnostic marker in the detection sites. Further, the system may also be able to compare the binding characteristic among a plurality of detection markers to order the level of effect of the stabilizing agents assayed on the binding characteristic between the detection agent and the diagnostic agent.

Systems and methods of screening biomarkers in bodily fluids

System and methods for the detection of biomarkers. In at least one embodiment of a system for the detection of a diagnostic marker in a body fluid of the present disclosure, the system comprises a diagnostic device comprising a plurality of test wells, wherein each test well is capable of containing at least one detection agent, a detection device capable of interacting with the diagnostic device, wherein the detection device is capable of detecting an interaction between the at least one detection agent and a diagnostic marker in at least one of the plurality of test wells, and a stabilization agent contained within at least one of the plurality of test wells, the stabilization agent capable of completely or substantially preventing the degradation or inactivation of the detection agent or the diagnostic marker.

Systems and methods for the detection of biomarkers

Systems and methods of biomarker analysis. In at least one embodiment of a system for determining the therapeutic potential of a therapeutic compound the present disclosure, the system comprises a detection platform, a computer database capable of receiving a plurality of binding characteristics, a processor operably coupled to the computer database and the detection platform. In at least one embodiment, the processor has and executes a software program operational to determine a binding characteristic of the detection agent and a stabilized diagnostic agent in each of the plurality of detection sites, compare the binding characteristic among each of the plurality of detection sites, wherein the comparison of binding characteristics is capable of determining the stabilizing agent with the greatest effect on the binding characteristic between the detection agent and the diagnostic agent, generate a binding record using the compared binding characteristics, and deliver the binding record to a recipient.

Systems and methods for biomarker analysis

Systems and methods for the detection of biomarkers. In at least one embodiment of a microarray system of the present disclosure, the microarray system comprises a microarray product comprising at least 100 diagnostic markers/cm, a microarray identifier, and a stabilizing agent, a control microarray product comprising a first specific binding pair member that binds to a first detectable label, and a processor for providing information regarding the identification and concentration of markers on the microarray based on the identity of the array provided by the microarray identifier.

At least one embodiment of a stabilizing system includes a stabilizing agent present in an amount or concentration sufficient to completely or substantially prevent or reduce degradation or inactivation of a glycosylated hemoglobin (HbA1c) in a body fluid and a detection agent capable of detecting the HbA1c.

Systems and methods for hemoglobin analysis

Certain poly(oxyalkylene) colorants are disclosed along with method of preparation thereof. A method of using these colorants as fluorescent security taggants is also disclosed.

Poly(oxyalkylene)ated colorants and their use as fluorescent security taggants

A method and apparatus for controlling access to a storage medium, such as an optically readable medium. Light sensitive or other materials that are adapted to change state and affect reading of a storage medium are used to control access to data that may be stored on optical medium and/or to control use of the medium.

Method and apparatus for controlling access to storage media

A copy-protected optical medium comprising transient optical state change security materials that demonstrating an optical state change when exposed to the wavelengths of from about 770 nm to about 830 nm.

Transient optical state change materials useful in copy-protected compact discs

Growing community of inventors

Durham, CT, United States of America

Rakesh Vig