Sun Pharmaceutical Industries Limited

Rakesh Thummar

Subhas Balaram Bhowmick

Rajamannar Thennati

Sudeep Kumar Agrawal

Amar Rana

Prashant Kane

Samarth Kumar

Milan Natvarbhai Thakkar

Kandarp Maheshkumar Dave

Shantaram Pawar

Jaydip Joshi

The present invention provides a stable, aqueous injectable solution comprising epinephrine or its pharmaceutically acceptable salt, a sulfite antioxidant, butylated hydroxyl anisole, an organic acid and a chelating agent, wherein the solution is free of an inorganic acid and an inorganic base. The invention also provides a method of treating the septic shock by intravenous administration of stable aqueous injectable solution comprising epinephrine or its pharmaceutically acceptable salt, a sulfite antioxidant, butylated hydroxyl anisole, an organic acid and a chelating agent, wherein the solution is free of an inorganic acid and an inorganic base.

Stable aqueous injectable solution of epinephrine

The present invention relates to a ready-to-administer parenteral dosage form of norepinephrine which comprises an aqueous solution of norepinephrine, having an anti-oxidant which is not a sulfite anti-oxidant, wherein the dosage form is stable at room temperature for prolonged period of time.

Parenteral dosage form of norepinephrine

The present invention relates to a sterile solution comprising: octreotide in the form of a pharmaceutically acceptable salt, present at a concentration equivalent to 2.0 mg/ml to 2.5 mg/ml of octreotide base, and at least one preservative in a pharmaceutically acceptable vehicle, wherein the sterile solution is present in an injection device.

Octreotide injection

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Baroda, India

Rakesh Thummar