Boehringer Ingelheim Pharmaceuticals, Inc.

Rajiv Sharma

John Robert Proudfoot

Pier Francesco Cirillo

Hidenori Takahashi

Sanxing Sun

Steffen Breitfelder

Usha R Patel

Eugene R Hickey

Alan David Swinamer

Thomas A Gilmore

Thomas M Kirrane

John R Regan

Neil Moss

Ming-Hong Hao

Karl D Hargrave

Charles Lawrence Cywin

Xiao-Jun Wang

Rajashekhar Betageri

Rajashehar Betageri

Mary Ann Hoermann

Thomas M Parks

Monica H Moriak

Disclosed are novel aromatic compounds which are useful for treating diseases or pathological conditions involving inflammation such as chronic inflammatory diseases. Also disclosed are pharmaceutical compositions containing and processes of making such compounds.

Compounds useful as anti-inflammatory agents

1-(4-aminophenyl)pyrazoles optionally substituted on the 3- and 5-positions of the pyrazole ring and on the amino group at the 4-position of the phenyl ring are disclosed and described, which pyrazoles inhibit IL-2 production in T-lymphocytes.

Substituted 1-(4-aminophenyl)pyrazoles and their use as anti-inflammatory agents

Disclosed are novel aromatic compounds of the formula (I) wherein G, X, Ar, L and Q are defined herein. The compounds are useful in pharmaceutic compositions for treating diseases or pathological conditions involving inflammation such as chronic inflammatory diseases. Also disclosed are processes of making such compounds.

Substituted 1-(4-aminophenly)triazoles and their use as anti-inflammatory agents

1-(4-Aminophenyl) indoles optionally substituted on the 2-,4-,5-,6- and 7-positions of the indole ring and on the amino group on the 4-position of the phenyl ring, which indoles inhibit IL-2 production in T-lymphocytes.

Substituted 1-(4-aminophenyl)indoles and their use as anti-inflammatory agents

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Ridgefield, CT, United States of America

Rajiv Sharma