Medtronic Vascular, Inc.

Rajesh Radhakrishnan

Keith Perkins

Samuel Robaina

Jeffery C Argentine

Darren Galligan

Matt Petruska

Adam Shipley

Tony Le

Terry Morgan

Jeffrey Mitchell

Matthew Petruska

The present technology relates generally to endovascular prostheses. More particularly, the disclosure relates to endovascular prostheses having an outer surface of a graft material thereof associated with a hydrogel composition, which may swell upon implantation within a blood vessel, thereby mediating various complications associated with endovascular procedures. The hydrogel compositions can also include various stabilizing polymers and active agents to further aid their use in the body.

Coated endovascular prostheses for aneurism treatment

A medical device includes an inflatable balloon defining an interior surface and an exterior surface, and a coating including a therapeutic agent disposed on the exterior surface of the inflatable balloon. The coating has a release transition temperature within a range from about 25&#xb0; C. to about 50&#xb0; C. When the temperature of the coating is below the release transition temperature, the coating retains at least a portion of the therapeutic agent on the exterior of the inflatable balloon. When the temperature of the coating is above the release transition temperature, the coating releases at least a portion of the therapeutic agent from the exterior of the inflatable balloon.

Drug coated inflatable balloon having a thermal dependent release layer

The present technology relates generally to endovascular prostheses. More particularly, the disclosure relates to endovascular prostheses having a graft material and a stent structure attached with a suture, or a seam formed by a suture, where the suture has a coating that expands upon exposure to body fluids. The expansion allows for the coating to fill suture holes in the graft material so as to reduce or eliminate endoleaks.

Coated sutures for reducing stent graft endoleaks

A scaffolded stent-graft includes a graft material comprising an inner surface and an outer surface. The inner surface defines a lumen within the graft material. The scaffolded stent-graft further includes a scaffold comprising a mesh coupled to the graft material at the outer surface. The scaffold is configured to promote tissue ingrowth therein. In this manner, the scaffold enhances tissue integration into the scaffolded stent-graft. The tissue integration enhances biological fixation of the scaffolded stent-graft in vessels minimizing the possibility of endoleaks and migration.

Stent graft with external scaffolding and method

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Petaluma, CA, United States of America

Rajesh Radhakrishnan