Zoetis Services LLC

Vertex Pharmaceuticals, Inc.

Chembridge Corporation

Zoetis LLC

Rajendran Vairagoundar

Richard Andrew Ewin

Paul D Johnson

Graham M Kyne

Timothy Allan Johnson

Michael P Curtis

Todd M Maddux

Tomasz Respondek

Matthew W Bedore

Jinglan Zhou

Sara Sabina Hadida Ruah

Sergey Zozulya

Fredrick Van Goor

Dennis James Hurley

Hayley Marie Binch

Lev T D Fanning

Tong Zhu

Timothy L Stuk

Alina Silina

Martyn Botfield

Alexander Chucholowski

Urvi Jagdishbhai Sheth

Vlad Edward Gregor

Anna Hazlewood

Jason Conrad Pickens

Susan M K Sheehan

Brian A Duclos

Yahua Liu

Mark R Cox

Susan Mary Kult Sheehan

Douglas Eric McGrath

Zheng Yan

Luyong Jiang

Tom L McTier

Charles Chamchoumis Mikel

Alexey Vyacheslavovich Anikin

Mohan Santhanam Thiruvazhi

Goverdhan Reddy Vavilala

Susan M Sheehan

Peter D J Grootenhuis

Peter Diederik Jan Grootenhuis

Edmund Lee Ellsworth

Thomas R Webb

Mehdi Michel Djamel Numa

Alisher B Khasanov

Mehdi Numa

Derek James Sheehan

Donald James Skalitzky

Vidyasagar Gantla

Aleksander Kadushkin

Danny Peter Claude McGee

Christopher Scott Knauer

Christoper S Knauer

Alexander Kadushkin

Timothy Johnson

Todd Maddux

Vidyasagar Reddy Gantla

Danny Peter Claude Mcgee

Alexey Anikin

Jason C Pickens

Douglas Eric Mcgrath

Charles Mikel

Richard A Ewin

Danny Peter Mcgee

Andrea K Haber-Stuk

Richard M Goodwin

Michael Curtis

Christopher S Knauer

Tom L Mctier

Denis Billen

Defined herein are immunomodulating Formula (1) compounds wherein R, R, R, R,

Immunomodulating urea azalides

The present invention provides cyclic depsipeptides of Formula (1), stereoisomers thereof, and veterinary acceptable salts thereof wherein each of R, R, R, R, L, and L, are as defined herein. The present invention also contemplates compositions and methods of treatment as an endoparasiticide with a Formula (1) compound.

Endoparasitic depsipeptides

The present invention provides cyclic depsipeptides of Formula (1), stereoisomers thereof, and veterinary acceptable salts thereof wherein each of R, R, R, R, L, and Lare as defined herein. The present invention also contemplates compositions, methods of treatment, and uses as a medicament to treat an animal for an endoparasitic infection with a Formula (1) compound.

Defined herein are immunomodulating Formula (1) compounds wherein R, R, R, R, Rand W are as defined herein, stereoisomers thereof, and pharmaceutically acceptable salts thereof; and compositions comprising said compounds. The invention also includes methods for treating an inflammatory and/or immunological disease or disorder in an animal by administering a therapeutically effective amount of a Formula (1) compound, stereoisomer thereof, and a pharmaceutically acceptable salt thereof; or use of said compound of Formula (1) to prepare a medicament for treating an inflammatory and/or immunological disease or disorder in an animal.

The present invention provides novel phenicol derivatives, their use for the treatment of infections in mammals, pharmaceutical compositions containing these novel compounds, and methods for the preparation of these compounds.

Phenicol antibacterial agents

The present invention provides novel phenicol derivatives, their use for the treatment of infections in mammals, pharmaceutical composition containing these novel compounds, and methods for the preparation of the compounds of formula I 

Phenicol antibacterials

Provided are compounds of the formula (I): or a stereoisomer, tautomer, salt, hydrate or prodrug thereof that modulate tyrosine kinase activity, compositions comprising the compounds and methods of their use. 

Tyrosine kinase inhibitors

The present invention relates to modulators of ATP-Binding Cassette ('ABC') transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.

Modulators of ATP-Binding Cassette transporters

The present invention provides novel cephalosporin derivatives of formula I, 

Cephalosporins useful as antibacterial agents

Modulators of ATP-binding cassette transporters

Provided are compounds of the formula (I): or a stereoisomer, tautomer, salt, hydrate or prodrug thereof that modulate tyrosine kinase activity, compositions comprising the compounds and methods of their use.

Tricyclic compound derivatives useful in the treatment of neoplastic diseases, inflammatory disorders and immunomodulatory disorders

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Kalamazoo, MI, United States of America

Rajendran Vairagoundar