Amgen Inc.

Innovationdock, Inc.

Rajendra V Deshpande

William James Boyle

Mei-Mei Tsai

Frank J Calzone

John Kevin Sullivan

Anna Hitz

John K Sullivan

Systems, devices, and methods for executing workflow instances of management of continuously changing data and queries. In one embodiment, a computing device may be configured to determine a set of related structured data comprising a key and associated value, where an associated ID and name for each related structured data of the set of related structured data may be determined. Additionally, a unique ID may be determined based on the determined associated ID and name. A match may then be determined for the set of core data elements based on a received message and an ordered list of results retrieved based on at least one of: the matched ID, the matched name, and the matched ID and name.

Devices and methods for implementing dynamic collaborative workflow systems

The present invention provides compositions and methods relating to or derived from anti-IGF-1R antibodies. In particular embodiments, the invention provides fully human, humanized, or chimeric anti-IGF-1R antibodies that bind human IGF-1R, IGF-1R-binding fragments and derivatives of such antibodies, and IGF-1R-binding polypeptides comprising such fragments. Other embodiments provide nucleic acids encoding such antibodies, antibody fragments and derivatives and polypeptides, cells comprising such polynucleotides, methods of making such antibodies, antibody fragments and derivatives and polypeptides, and methods of using such antibodies, antibody fragments and derivatives and polypeptides, including methods of treating or diagnosing subjects having IGF-1R-related disorders or conditions.

Compositions and methods relating to anti-IGF-1 receptor antibodies

The present invention provides compositions and methods relating to or derived from anti-IGF-1R antibodies. In particular embodiments, the invention provides fully human, humanized, or chimeric anti-IGF-1R antibodies that bind human IGF-R, IGF-1R-binding fragments and derivatives of such antibodies, and IGF-1R-binding polypeptides comprising such fragments. Other embodiments provide nucleic acids encoding such antibodies, antibody fragments and derivatives and polypeptides, cells comprising such polynucleotides, methods of making such antibodies, antibody fragments and derivatives and polypeptides, and methods of using such antibodies, antibody fragments and derivatives and polypeptides, including methods of treating or diagnosing subjects having IGF-1R-related disorders or conditions.

Compositions and methods relating to anti IGF-1 receptor antibodies

Selective binding agents of interferon-gamma (IFN&#x3b3;) are provided by the invention. More particularly, the invention provides for antibodies and antigen binding domains which selectively bind to IFN&#x3b3; and may be used to prevent or treat conditions relating to autoimmune and inflammatory diseases such as rheumatoid arthritis, systemic lupus erythematosus and multiple sclerosis. Nucleic acid molecules encoding said antibodies and antigen binding domains, and expression vectors and host cells for the production of same are also provided.

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Thousand Oaks, CA, United States of America

Rajendra V Deshpande