Asana Biosciences, LLC

Rajendra Kristam

Roger Astbury Smith

Bheemashankar A Kulkarni

Raghava Reddy Kethiri

Purushottam M Dewang

Nicholas James Laping

Chandregowda Venkateshappa

Rajesh Devraj

Aranapakam Mudumbai Venkatesan

Scott Kevin Thompson

Dhanalakshmi Sivanandhan

Srinivas Kasibhatla

The present application provides novel pyridine compounds and pharmaceutically acceptable salts or prodrugs thereof. Also provided are methods for preparing these compounds. These compounds are useful in inhibiting CYP17 activity by administering a therapeutically effective amount of one or more of the compounds to a patient. By doing so, these compounds are effective in treating conditions associated with CYP17 activity. A variety of conditions can be treated using these compounds and include diseases which are characterized by abnormal cellular proliferation. In one embodiment, the disease is cancer, such as prostate cancer.

Pyridine derivatives

The present application provides novel imidazole compounds and pharmaceutically acceptable salts thereof. Also provided are methods for preparing these compounds. These compounds are useful in inhibiting CYP17 activity by administering a therapeutically effective amount of one or more of the compounds to a patient. By doing so, these compounds are effective in treating conditions associated with CPY17 activity. A variety of conditions can be treated using these compounds and include diseases which are characterized by abnormal cellular proliferation. In one embodiment, the disease is cancer, such as prostate cancer.

Biaryl imidazole derivatives for regulating CYP17

Growing community of inventors

Noida, India

Rajendra Kristam