Lupin, Inc.

Rajan Goel

Rajender Kumar Kamboj

Neelima Sinha

Prathap Sreedharan Nair

Sudershan Kumar Arora

Navnath Popat Karche

Anil Kashiram Hajare

Majid Bashir Sayyed

Nabendu Saha

Sai Kumar Chakka

Azmi Reddy

Pravin Patil

K H Sreedhara Swamy

The present invention is related to novel 2-Amino-2-[8-(dimethyl carbamoyl)-8-aza-bicyclo[3.2.1]oct-3-yl]-exo-ethanoyl derivatives of the general formula (A), their tautomeric forms, their stereoisomers, their pharmaceutically acceptable salts, pharmaceutical compositions containing them, methods of making of the above compounds, and their use as Dipeptidyl Peptidase-IV (DPP-IV) Inhibitors, which are useful in the treatment or prevention of diseases particularly Type II diabetes, other complications related to diabetes and other pathogenic conditions in which DPP IV enzyme is involved. 

[object Object]

The present invention is related to novel compounds of the general formula A, their tautomeric forms, their stereoisomers, their pharmaceutically acceptable salts, pharmaceutical compositions containing them, methods of making of the above compounds, and their use as Dipeptidyl Peptidase-IV (DPP-IV) Inhibitors, which are useful in the treatment or prevention of diseases particularly Type II diabetes, other complications related to diabetes and other pathogenic conditions in which DPP IV enzyme is involved.

Compounds as dipeptidyl peptidase IV (DPP IV) inhibitors

Growing community of inventors

Pune, India

Rajan Goel