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Raisa Alexandrovna Arsatiants

Mikhail Markovich Gusyatiner

Vitaly Arkadievich Livshits

Nikolai Kazimirovich Yankovsky

Nelli Isaakovna Zhdanova

Evgeny Moiseevich Khurges

Tatyana Alexandrovna Bachina

Alla Valentinovna Belareva

Albert Fedorovich Sholin

Alexandr Konstantinovich Sokolov

Jury Dmitrievich Tsygankov

Tatyana Grigorievna Plotnikova

Jury I Kozlov

Tamara Mikhailovna Pozdnyakova

Vladimir Georgievich Debabov

Andrei Jurievich Chistoserdov

Irina Clegovna Shakalis

Irina Olegovna Shakalis

Vladimir G Debabov

Jury Ivancvich Kozlov

Sergei Vladimirovich Mashko

Rustem Saidovich Shakulov

Andrei J Chistoserdov

Ljudmila F Kozyreva

Evgeny Mciseevich Khurges

Andrei Jurievich Christoserdov

Tamara Mikhailcvna Pozdnyakova

Nelli Isaakcvna Zhdanova

Mikhail N Rozinov

Boris A Rebentish

Vera N Moshentseva

A bacterial strain ofis described which produces L-threonine, and is obtained by a process comprising transduction by bacteriophage P1 which bears a transposon which inactivates threonine dehydrogenase activity, and isolation of a transductant lacking threonine dehydrogenase activity.

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The present invention provides a method for deriving an strain which produces L-theronine from strain VNIIgenetika 472T23 by transducing with bacteriophage P1 which bears a transposon.

Bacterial strain of Escherichia coli BKIIM B-3996 as the producer of L-threonine

strains derived form,strain VNIIgenetika 472t23 and obtained by a process involving transduction by bacteriophage P1 which bears a transposon which inactivates threonine dehydrogenase activity and isolation of a transductant lacking threonine dehydrogenase activity are useful for producing L-threonine.

Escherichia coli strain and method for producing L-threonine

A bacterial strain of Escherichia coli BKIIM B-3996, a producer of L-threonine, containing a recombinant plasmid pVIC40 and deposited on Nov. 19, 1987 in the collection of microorganism cultures at the USSR Antiobiotics Research Institute under Reg. No. 1867.

Bacterial strain of Escherichia coli BKIIM B-3996 as the producer of

A bacterial strain of Escherichia coli BKIIM B-3996, a producer of L-threonine, containing a recombinant plasmid pVIC40 and deposited on Nov. 19, 1987 in the collection of microorganism cultures at the USSR Antibiotics Research Institute under Reg. No. 1867.

Bacterial strain of escherichia coli BKIIM B-3996 as the producer of

A method for constructing strains which produce aminoacids comprising combining of a DNA chromosome fragment of a donor microorganism containing genes controlling the synthesis of a selected aminoacid and having a mutation destroying the negative regulation of the synthesis of this aminoacid with a vector DNA molecule to form a hybrid DNA molecule. Use is made of a vector DNA molecule capable of providing amplification of the hybrid DNA molecule. The resulting hybrid DNA molecule is used for transforming cells of the recipient strain having the mutation blocking the synthesis of the selected aminoacid in this strain and the mutation partly blocking the related step of metabolism of this aminoacid to yield the strain capable of increased productivity of the selected aminoacid.

Method for preparing strains which produce aminoacids

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Moscow, Russia

Raisa Alexandrovna Arsatiants