Fraunhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung E.v.

Siemens Healthcare Gmbh

Norchip A/s

Institut Fur Mikrotecknik Mainz Gmbh

Institut Fur Mikrotechnik Mainz Gmbh

Rainer Gransee

Oliver Schmidt

Michael Bassler

Frank Karlsen

Klaus Stefan Drese

Tobias Baier

Manfred Ruehrig

Felix Schmitz

Tina Röser

Klaus-Stefan Drese

Eva Schaeffer

Frank Doffing

Frithjof Von Germar

Volkmar Stein

Silvio Kraus

Lars A Solli

Anja Gulliksen

Thomas Hansen-Hagge

Liv Furuberg

Vishnu Vatheriparambil Mohandas

Michael BAßLER

Xenia Strobach

Christiane Krempel

Jean-Michel Mehietang

A filter system is for the local attenuation of X-radiation. In an embodiment, the filter system includes a filter device, arranged in a beam path of an X-ray apparatus and including a channel arrangement, the channel arrangement including a multiplicity of channel sections extending in parallel on a plane; a supply device to provide a 2-phase fluid flow containing drops of an absorber liquid, to absorb X-radiation and a carrier liquid transparent to X-radiation; and a sorting section, including an input connected to the supply device, a first output connected to the channel arrangement, a second output, and a deflection device to direct individual drops of the absorber liquid to the first output or the second output.

Filter system for the local attenuation of X-radiation, X-ray apparatus and method for locally changing the intensity of X-radiation

A microvalve for controlling fluid flows, and a sealing device for sealing cavities in a microfluidic system, particularly in a lab-on-a-chip system, and a method for the production thereof. A sealing surface of a valve body, or a sealing element, respectively, rests on a sealing surface of a substrate and is pressed against the sealing surface of the substrate in a fluid-tight manner by means of a clamping element. The clamping element and/or the valve body, or the sealing element, respectively, are at least partially elastic.

Microvalve and sealing device for use in a microfluidics system, and method for the production thereof

A measurement channel for use in a microfluidic system, particularly a lab-on-chip system, having a first end at which a first gas permeable but liquid impermeable wall section is disposed which makes available a gas conduit, and a second end at which the measurement channel is connectable to at least one fluid conduit and at which an isolation or cutoff device is disposed, wherewith in the measurement channel a defined volume is included between the wall section and the isolation or cutoff device. A microfluidic structure is disclosed having a plurality of fluid conduits, and further having a valve for selectively connecting and/or blocking the fluid conduits, at least one of which fluid conduits is in the form of a measurement channel. A method of measuring and/or positioning a volume of a liquid in a microfluidic system, by a measurement channel is disclosed.

Microfluidic structure and method of measurement and/or positioning of a volume of a liquid

The present invention provides an integrated lab-on-a-chip device for carrying out a nucleic acid extraction process on a fluid sample containing cells and/or particles, the device comprising: (a) a sample inlet () for loading of a fluid sample, (b) a lysis unit () for lysis of cells and/or particles present in the fluid sample, (c) a reservoir of lysis fluid () for the lysis unit, (d) a nucleic acid extraction unit () downstream of the lysis unit, and (e) reservoirs of first washing buffer and eluant fluid () for the nucleic acid extraction unit, wherein the device further comprises (f) a mixing unit () downstream of the nucleic acid extraction unit, and (g) a source of mixing fluid () for the mixing unit. The reservoirs of lysis fluid, first washing buffer and eluant fluid may be provided parallel to one anther so that they may be actuated by a single pump.

Device for carrying out cell lysis and nucleic acid extraction

Growing community of inventors

Mainz, Germany

Rainer Gransee