Augusta University Research Institute, Inc.

Rafik Abdelsayed

Babak Baban

Mahmood Mozaffari

Jun Yao Liu

Glucocorticoid-induced leucine zipper protein (GILZ) peptide compositions and their methods of use in wound healing are disclosed herein. An exemplary GILZ peptide composition includes a GILZ fusion protein. The GILZ peptide compositions can be administered topically to wounds, for example in the form of a cream, ointment, or lotion. The GILZ peptide compositions can be used to treat acute wounds, induce wound healing in chronic wounds, and reduce scar formation.

GILZ formulations for wound healing

Methods for detection and diagnosis of Sj&#xf6;gren's Syndrome in a subject, determining the stage or progression of Sj&#xf6;gren's Syndrome in a subject, determining the effectiveness of a treatment for Sj&#xf6;gren's Syndrome, and selecting a subject for treatment for Sj&#xf6;gren's Syndrome are disclosed. The methods typically include measuring the level of one or more Sj&#xf6;gren's Syndrome biomarkers in a biological sample obtained from a subject. Biomarkers for Sj&#xf6;gren's Syndrome include, but are not limited to, GADD153 and Del-1.

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Augusta, GA, United States of America

Rafik Abdelsayed