University of California

Rafael Gòmez-Sjöberg

Peidong Yang

Ronald N Zuckermann

Brett Anthony Helms

Daojing Wang

Pan Mao

Joseph L DeRisi

Hung-Ta Wang

Rachel Ellen Gerver

Kurt S Thorn

Brian Cullen Baxter

Polly M Fordyce

Spectrally encoded microbeads and methods and devices for making and using spectrally encoded microbeads are provided. The disclosed methods and devices facilitate the preparation and use of microbeads containing multiple lanthanide nanoparticles, which microbeads have uniquely identifiable spectral codes. The disclosed microbeads, and the methods and devices for making and using same, find use in multiplexing and high-throughput biomarker analysis.

Spectrally encoded microbeads and methods and devices for making and using same

Systems, methods, and apparatus provide integration of microscopic imaging and liquid chromatography-mass spectrometry on a microfluidic device. In one aspect, an apparatus includes a first wafer, a second wafer, and an emitter. The emitter is disposed between the first wafer and the second wafer. The first wafer defines a sample input hole. The first wafer and the second wafer define a first channel, the first channel including a first end and a second end. The first end of the first channel is proximate the sample input hole. The first channel is configured to contain separation media. The second end of the first channel is proximate the emitter.

Microfluidic devices for liquid chromatography-mass spectrometry and microscopic imaging

Growing community of inventors

Menlo Park, CA, United States of America

Rafael Gòmez-Sjöberg