Ranbaxy Laboratories, Inc.

Ranbaxy Laboratory Limited

Radhakrishnan Gowri Shankar

Yatendra Kumar

Ram Chander Aryan

Anita Chugh

Kumar Hari Bhushan

The optically active compound, R (&#x2212;)-5-[2-[[2-(2-ethoxyphenoxy)ethyl]amino]propyl]-2-hydroxybenzenesulfonamide in good optical purity, a metabolite of the &#x3b1;-adrenergic blocking agent tamsulosin, and methods for the preparation thereof. Pharmaceutical compositions including the optically active compound and methods of treatment comprising administration of an effective &#x3b1;-adrenergic antagonistic amount of such compositions to mammals.

Tamsulosin derivative

The optically active compound, R(&#x2212;)-5-[2-[[2-(2-ethoxyphenoxy)ethyl]amino]propyl]-2-hydroxybenzenesulfonamide in good optical purity, a metabolite of the &#x3b1;-adrenergic blocking agent tamsulosin, and methods for the preparation thereof. Pharmaceutical compositions including the optically active compound and methods of treatment comprising administration of an effective &#x3b1;-adrenergic antagonistic amount of such compositions to mammals.

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Haryana, India

Radhakrishnan Gowri Shankar