Usv Private Limited

Radhakishnan Venkatasubramanian Tarur

Divya Lal Saksena

Nikhil Umesh Mohe

Chandrakesan Muralidharan

Lester John Lobo

Digamber Shripati Pawar

The present invention relates to an improved process for the large scale synthesis of cyclic heptapeptide using Fmoc solid phase synthesis technique. The described process assembles the peptide on a solid support resin by coupling to one another by peptide bonds to obtain a peptide wherein the coupling of cysteine to the resin employs a combination of solvents to reduce cysteine racemization. The process described relates to the use of C1-C4 alcohols as total substitute to organic nitriles thus making the process cost effective, non-toxic and eco-friendly.

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Mumbai, India

Radhakishnan Venkatasubramanian Tarur