Council of Scientific and Industrial Research

Radha Krishna Palakodety

Jhillu Singh Yadav

Santu Bandyopadhyay

Rakesh Kamal Johri

Subhash Chander Sharma

Siddhartha Roy

Bholanath Paul

Arun Bandyopadhyay

Mabalirajan Ulaganathan

Vasanta Madhava Sharma Gangavaram

Gangavaram Vasantha Madhava Sharma

Aditya Konar

Balaram Ghosh

Balram Ghosh

Gurdarshan Singh

Sakshi Balwani

Tulika Mukherjee

Dipak Kar

Tanima Banerjee

Debaprasad Jana

Kondireddi Ravinder Reddy

Ajit Chand Kunwar

Ravi Sankar Ampapathi

Jagannadh Bulusu

Ashok Kumar Saxena

Jayaprakash Pagadala

Sibabrata Mukhopadhyay

Mumu Chakraborty

A novel heterocyclic compound belonging to 'triazine-aryl-bis-indoles', useful for the treatment of asthma. The pathway by which this compound inhibits asthma is also demonstrated. The present invention also provides a process for the preparation of above compounds and their derivatives are presented.

Triazine-aryl-bis-indoles and process for preparation thereof

The present invention relates to a method for the treatment of bronchial asthma and chronic obstructive pulmonary disease (COPD) comprising administering to the patient suffering from asthma and COPD an effective dose of carbazole derivatives or salt thereof, optionally along with pharmaceutically acceptable excipients. Structural formula of the compounds of general formula 1 useful as phosphodiesterase-4 (PDE-4) enzyme inhibitors, inhibitor for signalling molecule for the treatment of asthma and asthma related diseases is given below:  Herbal route for the isolation of compound of general formula 1 from the bark of plantand chemical route for the preparation of such compounds from basic compounds such as vanillin is also reported.

Method for treatment of bronchial asthma

Nonnatural C-linked carbo-&#x3b2;-peptides with robust secondary structures, which involves the synthesis of a new class of &#x3b2;-peptides called C-linked carbo-&#x3b2;-peptides. The compounds are favorably disposed for the formation of stable helical structures and are useful as biologically active carbo-&#x3b2;-peptides. The new class of &#x3b2;-peptides have the following formulaThe new class of &#x3b2;-peptides are useful as biologically active molecules to disrupt biological interactions of proteins, for molecular design and to synthesize peptide libraries.

Non-natural C-linked carbo-&#x3b2;-peptides with robust secondary structures

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Andhra Pradesh, Indonesia

Radha Krishna Palakodety