Pluristem Ltd.

Rachel Ofir

Moran Meiron

Amir Toren

Nirit Drori-Carmi

Zami Aberman

Eytan Abraham

Esther Lukasiewicz Hagai

Dana Fuchs Telem

Niva Shraga Heled

Hoshea Yissachar Allen

Ariel Gilert

Adherent stromal cells cultured under three dimensional conditions are provided, characterized, and distinguished from adherent stromal cells cultured under two dimensional conditions.

Gene and protein expression properties of adherent stromal cells cultured in 3D

Described herein are methods of treating and preventing muscle wasting and muscle loss, using adherent stromal cells and conditioned medium produced thereby.

Methods and compositions for treating and preventing muscle wasting disorders

A method of treating ischemia in a subject in need thereof is disclosed. The method comprising administering to the subject a therapeutically effective amount of adherent cells of a tissue selected from the group consisting of a placenta and an adipose tissue, thereby treating the ischemia in the subject. A method of treating a medical condition requiring connective tissue regeneration and/or repair is also disclosed.

Adherent cells from adipose or placenta tissues and use thereof in therapy

A method of culturing adherent cells from a placenta or adipose tissue is disclosed. The method comprising culturing the adherent cells from the placenta or adipose tissue under 2 dimensional (2D) culturing conditions which allow cell expansion, the conditions comprising continuous passaging of the cells for at least 4 passages.

Adherent cells from placenta tissue and use thereof in therapy

A method of culturing adherent cells from a placenta or adipose tissue is disclosed. The method comprising culturing the adherent cells from the placenta or adipose tissue under 3 dimensional (3D) culturing conditions which allow cell expansion, the conditions comprising perfusion.

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Mitzpe Adi, Israel

Rachel Ofir