University of Michigan

Rachel Latvala

David J Mooney

Craig Reed Halberstadt

Petra Eiselt

Jon A Rowley

Julia Yeh

This invention is directed to a new approach to form porous hydrogel materials by first creating gas pockets in the gel and then removing this gas. The removal of the gas creates a porous material, and the initial incorporation of sufficient gas allows one to create a material with an open, interconnected pore structure. Advantageous features of the resulting materials, in addition to their interconnected pore structure, may include that the pore structure is maintained over extended time periods and that the gels maintain a high mechanical integrity that allows seeding with cells and implantation without destruction or compression of the material.

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Ann Arbor, MI, United States of America

Rachel Latvala