Yeda Research and Develpment & Co. Ltd

Other

Imec Vzw

Loma Linda University

Vrije Universiteit Brussel

Prosight Ltd.

Yeda Research and Development Ltd.

Yeda, Ltd.

Interuniversitair Micro-electronics Centrum Vzw (imec Vzw)

Rachel Chechik

Amos Breskin

Eric Beyne

Reinhard W Schulte

Vladimir A Bashkirov

Stefaan Tavernier

Walter Van Doninck

Guy Garty

Jamie Milligan

Stanislaw Majewski

Abraham Shanzer

Abraham Warshawsky

Michal Neeman

Bilha Schechter

Meir Weksler

Avi Simon

Zvi Paltiel

Alexei Buzulutskov

Marco Cortesi

Ehud Dafni

Amox Breskin

Sergei Shchemelinin

Sergi Shchemelinin

A method of analyzing a plurality of biopsy cores extracted from a plurality of respective biopsy locations in a prostate is disclosed. The method comprises: measuring a level of a chemical element in each of the biopsy cores, and generating a chemical element map of at least a portion of the prostate based on the levels and the respective biopsy locations. In some embodiments, the method determines at least one additional biopsy location for a future biopsy in the prostate.

Method of guiding prostate biopsy location

A nanodosimeter device () for detecting positive ions induced in a sensitive gas volume by a radiation field of primary particle, comprising an ionization chamber () for holding the sensitive gas volume to be irradiated by the radiation field of primary particles; an ion counter system connected to the ionization chamber () for detecting the positive ions which pass through the aperture opening and arrive at the ion counter () at an arrival time; a particle tracking system for position-sensitive detection of the primary particles passing through the sensitive gas volume; and a data acquisition system capable of coordinating the readout of all data signals and of performing data analysis correlating the arrival time of the positive ions detected by the ion counter system relative to the position sensitive data of primary particles detected by the particle tracking system. The invention further includes the use of the nanodosimeter for method of calibrating radiation exposure with damage to a nucleic acid within a sample. A volume of tissue-equivalent gas is radiated with a radiation field to induce positive ions. The resulting positive ions are measured and compared with a determination of presence or extent of damage resulting from irradiating a nucleic acid sample with an equivalent dose of radiation.

Nanodosimeter based on single ion detection

A nanodosimeter device ( ) for detecting positive ions induced in a sensitive gas volume by a radiation field of primary particle, comprising an ionization chamber ( ) for holding the sensitive gas volume to be irradiated by the radiation field of primary particles; an ion counter system connected to the ionization chamber ( ) for detecting the positive ions which pass through the aperture opening and arrive at the ion counter ( ) at an arrival time; a particle tracking system for position-sensitive detection of the primary particles passing through the sensitive gas volume; and a data acquisition system capable of coordinating the readout of all data signals and of performing data analysis correlating the arrival time of the positive ions detected by the ion counter system relative to the position sensitive data of primary particles detected by the particle tracking system. The invention further includes the use of the nanodosimeter for method of calibrating radiation exposure with damage to a nucleic acid within a sample. A volume of tissue-equivalent gas is radiated with a radiation field to induce positive ions. The resulting positive ions are measured and compared with a determination of presence or extent of damage resulting from irradiating a nucleic acid sample with an equivalent dose of radiation.

A delivery system and method for targeting a contrast agent to tissues and organs for improved diagnosis of tumors and for prognosis and follow-up of cancer therapy by X-ray imaging. The delivery system includes a conjugate or complex of a macromolecular carrier and a contrast agent selected from the group consisting of: (a) a compound having a heavy element with an atomic number in the range of 75 to 92, and (b) a compound having an element with a property of an abrupt change in its X-ray attenuation coefficient within the energy range used for radiography, said macromolecular carrier of said conjugate or complex being optionally linked to a specific tissue marker molecule.

X-ray imaging of tumors with dextran carrier of platinum compounds

This invention discloses a thin-film-coated photocathode, including a photocathode formed of first material consisting of potassium cesiuin antimonide and a thin-film coating of a second material consisting of cesium bromide (CsBr).

Protection of photocathodes with thin film of cesium bromide

Imager or particle or radiation detector and method of manufacturing the same

The present invention may provide a particle detector or imager which may be used for accurate recording of medical (2-D) X-ray images. The imager includes at least one detector panel. The detector panel includes a microgap detector with an array of pixel electrodes of a novel form. Each pixel electrode is insulated from a planar cathode by means of an insulating layer. Each pixel electrode is connected to an underlying contact by means of a via hole in the insulating layer. The insulating layer is preferable conformal with the electrodes. The underlying contact is connected to an electronic measuring element which preferably lies underneath the electrode and is about the same size as the electrode. The measuring element may be a storage device, a digital counter or similar. A switching transistor is connected to the measuring device. The switching transistor may be a thin film transistor. Alternatively, both measuring element and transistor may be formed in a single crystal semiconductor, e.g. a VLSI, and a complete imager formed from several detector panels in an array. The drift electrode of the microgap detector preferably includes a photocathode. The photocathode may be directly evaporated onto a phosphor.

Imager or particle detector and method of manufacturing the same

Apparatus for digital imaging including at least one electron multiplier arranged to receive beta radiation from a sample, apparatus for collimating the beta radiation without totally blocking all radiation from any location within a given region of interest on the sample, and readout electrodes operative in response to electrons from the electron multiplier to provide a first output indication of the incidence and location of beta radiation from the sample.

Apparatus for digital imaging

An X-ray detector including a photocathode arranged to receive X-ray radiation and being operative to provide in response thereto an output of electrons, and at least one electron multiplier operative at subatmospheric pressure and in response to the output of electrons from the photocathode to provide an avalanche including an increased number of electrons.

X-ray imaging detector with a gaseous electron multiplier

Apparatus for radiographic imaging including a multistage avalanche chamber receiving radiation from a multiplicity of radiation point sources on a sample and providing a multiple photon output indicative of the path of the emitted radiation through the avalanche chamber, image intensification apparatus receiving the photon output of the avalanche chamber, a camera receiving an output from the image intensification apparatus; image processing apparatus for receiving the camera output and carrying out a vector analysis on the information contained in the camera output in order to determine the location of the radiation emitting point source on the sample.

Apparatus for radiographic imaging

Growing community of inventors

Moshav Beit Hanan, Israel

Rachel Chechik