National Guard Health Affairs

King Saud Bin Abdulaziz University for Health Sciences

King Abdullah International Medical Research Center

King Abdullah Inetrnational Medical Research Center

Rabih Omran Al-Kaysi

Mohamed Boudjelal

Atef Nehdi

Imadul Islam

Rizwan Ali

Bandar Alghanem

Methods of preparing hollow charge transfer co-crystals with reproducible habits and morphology are disclosed. The disclosed methods utilize surfactant to guide the crystal growth in aqueous solutions. The size and shape of the co-crystal can be controlled by the surfactant used, the concentration of the surfactant, and electron donor and electron acceptor, incubation temperature, and mixing condition.

Method for controlling charge-transfer co-crystals growth

Compounds, methods of synthesis, and methods of cancer treatment by arylidene-1,3-dioxane-4,6-diones. A Meldrum's acid-based chemistry and hybrid solid-liquid method. The method includes protection of ketone and aldehyde components and simultaneous immobilization on the solid phase, introduction of substituents, grafts and derivatives compatible with the protection, detachment and restoration of active carbonyl reactivity, reaction of ketone library with malonate, reacting of the products with the aldehyde library in liquid phase and separation of the products by preparative HPLC.

Anticancer 1,3-dioxane-4,6-dione derivatives and method of combinatorial synthesis thereof

A method is described for exfoliating a microcrystal of an anthracene derivative by irradiation with short pulses of light having a wavelength of 220-420 nm. The irradiation induces a cis-trans isomerization of the anthracene derivative in a part of the microcrystal, which leads to the separation of an outer layer having a thickness of 200-600 nm. The exfoliated microcrystal may be irradiated again with pulses of light of a same or different wavelength.

Microcrystal exfoliation by UV light irradiation

Spontaneous peeling of tetragonal microcrystals with short pulses of UV-light

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Riyadh, Saudi Arabia

Rabih Omran Al-Kaysi