Other

UniversitÈ Laval

Mission Pharmacal Company

Infectio Recherche Inc.

Rabeea F Omar

Michel G Bergeron

Mary Ann Walter

Jian Gao

Andrew Desormeaux

André Désormeaux

Julianna Juhasz

The present disclosure provides novel formulations suitable for the intravaginal delivery of tinidazole, as well as methods of using the same.

Formulations for the treatment of vaginal disorders

This invention relates to a vaginal/ano-rectal applicator for the uniform delivery of any topical formulations to treat and/or prevent any infection and/or abnormal conditions of mucosa cavity caused by any pathogen and/or disease. The present applicator comprises a longitudinally extending body that has proximal and distal ends. The proximal end is located close to the external site of a mucosal cavity accessible to a user. The body has external perforations, made as a series of slots or holes, for uniform distribution of any formulation to be delivered to the user's mucosal cavity. Upon insertion of the applicator and expulsion of the formulation in the mucosal cavity, the formulation, which is contained in a reservoir, travels through a diffusion channel having a small volume, prior to being expelled through the perforations.

Applicator for the delivery of topical formulations into mucosal cavities

This invention relates to formulations for the prevention of infection and/or abnormal conditions of mucosae and/or skin caused by any pathogen and/or any disease, and more particularly for the prevention of sexually transmitted infections specially HIV and HSV. This invention also relates to formulations for the treatment of infection and/or abnormal conditions of skin and/or mucosac and more particularly for the treatment of herpetic lesions. The formulations could be used as a prophylactic agent to prevent accidental infection of health care workers. The formulations could be used for the healing and/or treatment of bum wounds and prevention of further infection. This invention also relates to the development of a unique vaginal/ano-rectal applicator for the uniform delivery of any topical formulations to treat and/or prevent any infection and/or abnormal conditions of mucosa cavity caused by any pathogen and/or disease.

Formulations for the prevention or the treatment of diseases affecting mucosae or skin, or for pregnancy prevention, and an applicator for the delivery of topical formulations into mucosal cavities

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CA

Rabeea F Omar