Multi-magnetics Inc.

R Terry Thompson

Frank S Prato

Robert Z Stodilka

D James Koropatnick

Donna E Goldhawk

Benoit Lewden

Neil Gelman

Rene Figueredo

Jean Theberge

The invention provides an improved modified magnetosome that contains more iron therein with the combination of the expressed genes. This is achieved by co-expression of (a) one or more bacterial magnetotactic genes to amplify iron uptake, compartmentalization and biomineralization in cells, with (b) one or more mammalian iron handling proteins that together augment(s) and/or regulate the cells iron pool. As a result, mammalian cells or bacterial cells that are transfected or transformed, respectively, can be more effectively tracked using various imaging technologies.

Co-expression of magnetotactic bacterial genes and genes encoding iron handling proteins in cells

A hybrid medical imaging system comprises a nuclear medicine imaging subsystem for capturing an image of a target region of a subject, a magnetic resonance imaging (MRI) subsystem for capturing an MRI image of the target region based on at least one MRI parameter and processing structure communicating with the subsystems. The processing structure processes the MRI image to estimate attenuation within the target region and uses the estimated attenuation to correct the image captured by the nuclear medicine imaging subsystem.

System and method for correcting attenuation in hybrid medical imaging

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London, Canada

R Terry Thompson