C. R. Bard, Inc.

R Michael Casanova

Chandrashekhar Prabhakar Pathak

Dnyanesh A Talpade

Robert G Lerdahl

A method of making an intracorporeal marker, including the method steps of providing a core having a first material with porous hydroxyapatite; and completely covering the core an outer region having a second material with less porous hydroxyapatite, wherein ultrasonic or radiative imaging reveals a difference between the marker and tissue.

Multiple imaging mode tissue marker

A marker includes a core and an outer region. The core has a first material with porous hydroxyapatite. The outer region completely covers the core, and has a second material with less porous hydroxyapatite, wherein ultrasonic or radiative imaging reveals a difference between the marker and tissue.

A stent graft is disclosed and can include a stent and a graft engaged with the stent. The graft can include an inner surface and an outer surface. Further, at least one of the inner surface and the outer surface can include a plurality of protrusions as viewed in cross section extending through a longitudinal axis.

Kink resistant stent graft

An intracorporeal tissue marker includes a first material comprising a core region of the marker. The first material has a first density. A second material completely surrounds the first material. The second material is distinct from the first material and has a second density. The first density of the first material is lower than the second density of the second material.

An intracorporeal marker for marking a site within living tissue of a host having a body of porous hydroxyapatite whose physical properties permit the body to be distinguished from human soft tissue under visualization using ultrasonic and radiation imaging modalities.

A graft device comprising a layer of synthetic non-metallic material having a first surface and a second surface spaced apart from the first surface. The device further includes a radiopaque marker at least partially embedded in the layer.

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Tucson, AZ, United States of America

R Michael Casanova