Google Inc.

Duke University

Dana-farber-cancer Institute Inc.

Whitehead Institute for Biomedical Research

R Michael Angelo

Andrew Stephen Tomkins

Simon Tong

David Braginsky

Matthew K Gray

Russell J Ryan

Roni Fischman Zeiger

Jeremy Ginsberg

Namrata U Godbole

Thomas A Lasko

Jonathan S Stamler

Todd R Golub

Pablo Tamayo

April S Brown

Scott D Wolter

William V Lampert

Sridhar Ramaswamy

A sensor comprising an electronic circuit electrically coupled to a type III-V semiconductor material, for example indium arsenide (InAs) and an antibody contacting the type III-V semiconductor material. The sensor produces measurable N changes in the electrical properties of the semiconductor upon antibody-antigen binding events. Electrical properties measurable by the electronic device may include resistivity, capacitance, impedance, and inductance. A method of detecting an antigen using sensors of the invention. A method of detecting a reaction of an analyte to a stimulus using sensors of the invention. Sensor arrays comprising multiple sensors of the invention.

Sensors incorporating antibodies and methods of making and using the same

A system receives a search query from a user and searches a group of repositories, based on the search query, to identify, for each of the repositories, a set of search results. The system also identifies one of the repositories based on a likelihood that the user desires information from the identified repository and presents the set of search results associated with the identified repository.

Determination of a desired repository for retrieving search results

Amount of combined nitric oxide or nitric oxide presented as iron nitrosyls in a blood sample is determined by directing a low power electromagnetic radiation beam at a blood sample to liberate nitric oxide gas, dissolving the liberated nitric oxide gas and electrochemically detecting amount of dissolved nitric oxide gas.

Method for liberating and detecting nitric oxide from nitrosothiols and iron nitrosyls in blood

Amount of combined nitric oxide or nitric oxide present as iron nitrosyls in a blood sample is determined by directing a low power electromagnetic radiation beam at a blood sample to liberate nitric oxide gas, dissolving the liberated nitric oxide gas and electrochemically detecting amount of dissolved nitric oxide gas.

Methods, systems, and apparatus, including computer programs encoded on computer storage media, for identifying entities using search results. One of the methods includes determining that a first search query includes a respective text reference to each of one or more predetermined attributes, wherein each attribute is associated with a first entity type; obtaining search results for the first search query from a search engine, the search results identifying a plurality of resources; identifying entities of the first entity type that are related to any of the plurality of resources identified by the search results; and selecting names of one or more of the identified entities of the first entity type to include in a response to the first search query.

Identifying entities using search results

Methods, systems, and apparatus, including computer programs encoded on computer storage media, for identifying entities using search results. One of the methods includes determining that a search query includes a respective text reference to each of one or more predetermined attributes, wherein each attribute is associated with an entity type; obtaining search results for the search query from a search engine, each search result identifying a respective resource; for each of a plurality of the obtained search results, determining an initial score for each of a plurality of entities of the entity type based on occurrences of names of the entity in the resource identified by the search result; generating a final score for each of the entities based on the initial scores; and selecting one or more names of entities of the entity type to include in a response to the search query based on the final scores.

Methods, systems, and apparatus, including computer programs encoded on computer storage media, for identifying entities using search results. One of the methods includes the actions of determining that a first search query includes a respective text reference to each of one or more predetermined attributes, wherein each attribute is associated with a first entity type; for each of a plurality of entities of the first entity type, generating a combined search query that includes the first search query and a name of the entity; obtaining search results for each of the plurality of entities using the combined search query for each respective entity; and using the obtained search results to generate combined search results to include in a response to the first search query.

Methods, systems, and apparatus, including computer programs encoded on computer storage media, for identifying entities using search results. One of the methods includes the actions of determining that a first search query includes a respective text reference to each of one or more predetermined attributes, wherein each attribute is associated with a first entity type; generating a second search query including the first search query and one or more terms that refer to the first entity type; and evaluating search results obtained for the second search query to select one or more names of entities of the first entity type to include in a response to the first search query.

Determination of a desired repository

A system receives a search query from a user and searches a group of repositories, based on the search query, to identify, for each of the repositories, a set of search results. The system also identifies one of the repositories based on a likelihood that the user desires information from the identified repository and presents the set of search results associated with the identifies repository.

Sets of genetic markers for specific tumor classes are described, as well as methods of identifying a biological sample based on these markers. Also described are diagnostic, prognostic, and therapeutic screening uses for these markers, as well as oligonucleotide arrays comprising these markers.

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Berkeley, CA, United States of America

R Michael Angelo