Alk-abello A/s

R Ikke Morkeberg

Hans-Henrik Ipsen

Tine Charlotte Beck

Soren Bogestrand

Niels Johansen

The invention relates to a method of evaluating the immunological status of a subject comprising the steps of 1) determining the content of an antibody in a liquid sample from the subject using an immunoassay, wherein the reaction between the antibody of the sample and a ligand in the form of an antigen, an antibody or a hapten, the ligand being directed to the Fab region of the sample antibody, is carried out in the presence of other constituents of the sample to obtain a measurement , 2) determining the content of an antibody in the liquid sample using an immunoassay, wherein the reaction between the antibody of the sample and a ligand in the form of an antigen, an antibody or a hapten, the ligand being directed to the Fab region of the sample antibody, is carried out in the absence of other constituents of the sample to obtain a measurement , and 3) interrelating measurements and to express the interference and using the interference as a parameter for evaluating the immunological status of the subject.

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Nærum, Denmark

R Ikke Morkeberg