Abbott Laboratories Corporation

Other

R Hayes Helgren

Wayne F Adolf

Walter T Szempruch

James T Renick

Mark E Larkin

David E Kramer

Warren P Frederick

Robert J Kruger

Joaquin Mayoral

Roman W Siczek

Kenneth J Timmons

Charles C Valentincic

Brad A Schmolesky

Gary Lawrence Johnston

Timothy P Henning

Thomas G Schapira

David Dean Cunningham

Hrishikesh Choudhury

Neal T Sleszynski

Kenneth A Hsu

Kenneth S Johnson

Jill M Geist

Ray A Winfield

Laura S Morici

Susan B Brontman

Thomas E Mattice

A housing that can be used to form and maintain a fluid-tight connection between a container and a medical device. The housing comprises an internal receiving surface circumscribing a cavity into which a fitting of the medical device can be inserted. The internal receiving surface comprises a first wall portion having a first contact annulus and a second wall portion having a second contact annulus. Upon insertion of the fitting into an opening in the cavity of the housing, the fitting forms a primary seal with the first contact annulus and a secondary seal with the second contact annulus. The primary seal is formed as the surface of the fitting contacts the first contact annulus of the internal receiving surface of the housing. The secondary seal is formed as the surface of the fitting contacts the second contact annulus of the internal receiving surface of the housing.

Housing capable of connecting a container to a medical device

A reseal is partially perforated by stretching the reseal membrane, establishing contact between one side of the membrane and an anvil, and by effecting partial penetration of the membrane with at least one cutting edge from the other side of the membrane to a predetermined distance from the anvil. Multiple partial perforations may be made with one or more cutting edges.

Reseal with a partial perforation and method and apparatus for creating

Medical drug formulation and delivery system includes a reverse osmosis device for purifying water from a source comprising a housing having an inlet for passage of water from the source, a first outlet for passage of purified water from the housing and a second outlet for passage of waste water remaining after purification. A first reverse osmosis multilayer assembly is disposed within the housing in fluid communication with the inlet for purification of at least a first portion of the water from the source. Water treatment chemicals can be positioned in a core about which the first reserve osmosis multilayer assembly is wound. The treatment chemicals are in fluid communication with the first reverse osmosis multilayer assembly to receive the first purified portion of water and for removal of at least chemical contaminants therefrom. A second reverse osmosis multilayer assembly is also wound on the core and is in fluid communication with the water treatment chemicals to receive the chemically purified water for purification of at least a second portion thereof. The second reserve osmosis multilayer assembly is in fluid communication with the first outlet so as to permit passage of the second portion of purified water therethrough. In one preferred embodiment, the first and second reverse osmosis assemblies are formed integrally in a side by side configuration. In an alternative embodiment, they are rolled about the core in an interleaf configuration.

Water purification using reverse osmosis device for formulation of

The present invention relates to a pointed adapter which enables a blunt entry device such as a blunt cannula to readily penetrate an elastomeric closure such as a conventional vial stopper. The adapter includes a breakaway collar which initially protects the adapter point from touch contamination and from accidental stick to the user.

Pointed adapter for blunt entry device

A valve including a substantially rigid cannula and a valve member positioned for operable communication with the cannula. The valve member is formed from a substantially resilient material, having a slit extending therethrough, and movable with respect to the cannula between a first closed position and a second open position. The slit is substantially closed by the resiliency of the material of the valve member when the valve member is positioned in the first closed position and the cannula cooperates to extend through the slit during movement of the valve member from the first closed position to the second open position to establish a fluid flow path through the cannula and the valve member. A sealing member is also provided independent from a flow of fluid within the fluid flow path to provide positive sealing of the slit when the valve member is positioned in the first closed position.

Valved intravenous fluid line connector

The present invention relates to a sterile form, filled and sealed flexible solution container and an attached port assembly that allows for the sterile dispensing of the solution. In particular, the present invention relates to a sterile formed, filled and sealed flexible solution container and a sterile administration port assembly which is attached without interrupting the complete sealing of the hermetically sealed fluid container and which allows for the sterile packaging, storage and delivery of a sterile medical solution without heat degradation or oxygen permeation.

Sterile formed, filled and sealed flexible container

Medical drug formulation and delivery system includes a reverse osmosis device for purifying water from a source comprising a housing having an inlet for passage of water from the source, a first outlet for passage of purified water from the housing and a second outlet for passage of waste water remaining after purification. A first reverse osmosis multilayer assembly is disposed within the housing in fluid communication with the inlet for purification of at least a first portion of the water from the source. Water treatment chemicals can be positioned in a core about which the first reserve osmosis multilayer assembly is wound. The treatment chemicals are in fluid communication with the first reverse osmosis multilayer assembly to receive the first purified portion of water and for removal of at least chemical contaminants therefrom. A second reverse osmosis multilayer assembly is also wound on the core and is in fluid communication with the water treatment chemicals to receive the chemically purified water for purification of at least a second portion thereof. The second reserve osmosis multilayer assembly is in fluid communication with the first outlet so as to permit passage of the second portion of purified water therethrough. A method of forming a reverse osmosis device, a peritoneal dialysis treatment system and alternative treatment systems incorporating such a device as well as corresponding methods of treatment are also disclosed.

Peritoneal dialysis system using reverse osmosis purification device

The present invention relates to a sterile form, filled and sealed flexible solution container and an attached port assembly that allows for the sterile dispensing of the solution.

Method for forming, filling and sealing a sterile flexible container

The present invention relates to a pointed adapter which enables a blunt entry device such as a blunt cannula to readily penetrate an elastomeric closure such as a conventional vial stopper. The adapter also includes a collar which initially protects the adapter point from touch contamination and from accidental stick to the user.

A reseal member having a preferentially weakened central portion, and a method of its manufacture through the application of ultrasonic energy. The reseal is for use with an associated blunt cannula. The reseal comprises a central region and a peripheral region. The central region has a predetermined thickness and includes, in the direction of thickness, a weakened portion extending at least partially therethrough. The upper and lower surface portions of the reseal are continuous and unbroken. A method of forming the weakened central portion includes the steps of positioning the reseal member in an ultrasonic energy generating device, placing the member in compression, and imparting a predetermined amount of ultrasonic energy, in the form of vibrational energy, into the reseal member. The present reseal member can be used for solution vials and containers, tubing set Y-sites, and similar applications.

Method of forming a reseal member for use with blunt cannulas

A system for tilting and lifting a device includes three pulleys and a cable. A portion of the cable is adjustable. Two of the pulleys are connected to a stationary surface and the third pulley is connected to the object. One end of the cable is connected to the object and the other end provides for the application of force.

Object rotating, lifting and storage system

A sensor for measuring the concentration of an analyte in a solution is disclosed. The sensor may be adapted for use as either an amperometric or a potentiometric sensor. It includes a membrane having a biologically active protein immobilized within. The membrane is attached and reliably sealed to a housing by means of ultrasonic welding, either directly or indirectly. Further, the membrane may be compressed to a fraction of its original dimensions. Metallic parts of the device may, optionally, be physically isolated from the sample solution to reduce corrosion. These features operate synergistically so that the claimed device exhibits relatively fast response and recovery times, is reliably leak-proof, and may be constructed in relatively small sizes.

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Mundelein, IL, United States of America

R Hayes Helgren