Medtronic Minimed, Inc.

Edh Biotech Corp

Quyen Ong

Ashwin K Rao

Thomas Meehan

Michael E Miller

Rebecca K Gottlieb

Sarnath Chattaraj

Poonam S Gulati

Mohsen Askarinya

Akhil Srinivasan

Guangping Zhang

Melissa Tsang

Chi-En Lin

Xin Heng

Inthirai Somasuntharam

Michael N Missaghi

Carlos E Maldonado

Ariel Reider

The invention provides amperometric analyte sensor systems comprising one or more electrodes designed to monitor in vivo levels of 3-hydroxybutyrate (and optionally glucose as well) in order to facilitate the management of diabetic ketoacidosis. The invention further includes compositions, elements and methods useful with such amperometric analyte sensor systems.

Sensors for 3-hydroxybutyrate detection

Described here are patches and methods for measuring glucose in sweat (and tears and the like). In general, the patches comprise an adhesive layer adapted to bond to skin of an individual, a substrate layer disposed over the adhesive layer and comprising a glucose sensing complex including a chromogen that changes color in the presence of certain concentrations of glucose, and a cover. In typical embodiments, the substrate layer has elements formed to direct and accumulate sweat that migrates from the skin of the individual to the glucose sensing complex. Methods of using the invention can comprise cleaning the skin surface, collecting sweat in a patch comprising this microfluidic constellation of elements, and observing concentrations of glucose collected in the sweat, for example either visually, or by using a smartphone or other computer processing device.

Colorometric sensor for the non-invasive screening of glucose in sweat in pre and type 2 diabetes

The present application discloses a targeting composition that actively targets chitin-like substances, such as those found in fungi, protists, arthropods, Alzheimer's plaques, etc. Methods are disclosed for preparation of chitin-targeted drug delivery vehicles composed of the targeting composition and one or more bioactive compounds.

Targeted delivery of anti-fungal agents

The present application discloses a targeting composition that actively targets chitin-like materials, such as those found in fungi, a drug delivery vehicle comprising a micelle that comprises the targeting composition and one or more anti-fungal drugs, and methods of using the drug delivery vehicle.

Targeting delivery of anti-fungal agents

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Arcadia, CA, United States of America

Quyen Ong