Eisai Inc.

Mgi Gp, Inc.

Other

Guilford Pharmaceuticals, Inc.

Eisai Corporation of North America

Wuxi Weiyi Zhinengkeji, Inc.

Qun Liu

Weizheng Xu

Vincent Jacob Kalish

Jia-He Li

Jie Zhang

Amy Xing

Tianxin Wang

Pavel Majer

Takashi Tsukamoto

Doris Stoermer

Shazhou Zou

Sha Zhou Zou

Bunda Hin

The present invention provides compounds which inhibit poly(ADP-ribose) polymerase ('PARP'), compositions containing these compounds and methods for using these PARP inhibitors to treat, prevent and/or ameliorate the effects of the conditions described herein.

Compounds, methods and pharmaceutical compositions for inhibiting PARP

Methods and compounds are provided to improve the desorption and ionization of analyte for mass spectrometry analysis. More specifically, it is for laser desorption/ionization mass spectrometry. The method uses photon energy absorbing molecules that can bind with analyte either temporarily or permanently to improve the desorption and ionization of analyte. The photon energy absorbing molecules can be positively charged or negatively charged.

MALDI analysis using modified matrices with affinity groups for non-covalent binding with analytes

Methods and compounds are provided to improve the desorption and ionization of analyte for mass spectrometry analysis. More specifically, it is for laser desorption/ionization mass spectrometry. The method uses photon energy absorbing molecules that can bind with analyte either temporarily or permanently to improve the desorption and ionization of analyte.

MALDI analysis based on derivatized matrices forming covalent bonds with analyte molecules

This invention relates to new compounds, pharmaceutical compositions and diagnostic kits comprising such compounds, and methods of using such compounds for inhibiting NAALADase enzyme activity, detecting diseases where NAALADase levels are altered, effecting neuronal activity, effecting TGF-&#x3b2; activity, inhibiting angiogenesis, and treating glutamate abnormalities, neuropathy, pain, compulsive disorders, prostate diseases, cancers and glaucoma.

Hydroxamic acids and acyl hydroxamines as naaladase inhibitors

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Columbia, MD, United States of America

Qun Liu