Idexx Laboratories, Inc.

Idexx Corporation

Quentin J Tonelli

Randall G Groat

Thomas P O'Connor

Philip R Andersen

Erwin F Workman, Jr

Philip L McMahon

Michael Monn

Paul C Brooks

Larry Chaney

Michael P Monn

A method for detecting a parasitic worm infection of the digestive tract of a mammal. The method includes detecting the binding of a worm antibody to a worm antigen present in the soluble portion of a fecal sample of infected mammals.

Detection of analytes in fecal samples

A method and device for determining a feline immunodeficiency virus infection or vaccination in an animal. The method includes contacting a biological sample from a felid with various FIV polypeptides and determining the binding of antibodies in the sample to the polypeptides. The determination of whether an animal is infected with FIV or has been vaccinated against FIV can be determined by measuring the animal's immune response to an FIV env polypeptide. A device for detecting FIV antibodies is provided.

Method and device for detecting feline immunodeficiency virus

An isolated envelope polypeptide of Feline Immunodeficiency Virus (FIV) that reacts specifically with a gp-130 envelope specific monoclonal antibody. Immunoassays using such isolated polypeptides are also disclosed.

Polypeptides of feline T-cell lymphotropic lentivirus

Purified polypeptides of Feline Immunodeficiency Virus (FIV) are disclosed. The polypeptides of the invention include p10, p15, p26, gp40, gp100 and gp130.

Polypeptides of feline T-cell lymphotrophic lentivirus

A method for detecting the presence of antibody to FIV in a biological sample. The method includes the steps of providing a first antigen having a first epitope recognized by the antibody, the first antigen being detectable; contacting the first antigen with the sample under conditions under which the antibody can bind to the first antigen to form an immune complex; and detecting the immune complex. An ELISA test for FIV, using purified FIV antigen, is also described.

Detection of both an antibody and an antigen in a single sample aliquot

In one aspect, a kit for the semi-quantitative measurement, in a liquid sample, by competitive immunoassay, of a first member of a specific binding pair, the kit including a solid support bearing

Immunoassays having at least two test spots and reference spot

Disclosed is a dipstick test device for detecting an analyte in a liquid sample by treating the analyte with at least one liquid reagent to form a detectable reaction product. The device includes: a) an aqueous impermeable, aqueous insoluble reaction zone, adapted to retain the detectable reaction product; and b) a control absorbent above, and in liquid-transferring relation with, the reaction zone. The control absorbent has a predetermined, limited liquid-absorbing capacity, and the dipstick is sized and configured for insertion into a vessel containing the sample, with the control absorbent oriented above the reaction zone, so that the control absorbent fills to capacity with sample and the reaction zone incubates with the sample. The device may further include an absorbent reservoir which can be moved into liquid transferring contact with the reaction zone.

Dipstick test device including a removable filter assembly

Monoclonal antibodies specific for an epitope of an FIV-encoded antigen.

Monoclonal antibodies to feline-T-lymphotropic lentivirus

A method of assaying a sample of whole blood for one member of a specific binding pair, the method involving treating the sample with salt to alter the red blood cells in the sample to decrease their ability to pass through filter media, exposing the resulting sample to a filter which retains the red blood cells but allows the passage therethrough of filtrate of the sample containing the member of the specific binding pair, and measuring the member of the filtrate.

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Portland, ME, United States of America

Quentin J Tonelli