Avent, Inc.

Edwards Lifesciences Corporation

Kimberly-clark Worldwide, Inc.

Quang Ngoc Vu

Tri D Tran

Siddharth Desai

Deepak R Gandhi

Michael Bukin

Giuseppe Sacca

Gonzalo German Angelico

Ashley Akemi Ishigo

Kokeb Tefera

Kim D Nguyen

Michael C Murad

Ronaldo C Cayabyab

Brendan Michael Dalbow

Gil Senesh

Michael R Bialas

Jeanette Jasmine Corona

Lien Huong Thi Hoang

Kristen Hicks

Grant Jason Gangeness

Taylor Michael Winters

Jennifer Marie Reitmajer

Carla Susana Cerqueira

Victoria Mariko Low

Vicky Hong Do

Andrea Fernandez

Karl J Britzman

Haley Nicole Whitehead

Shannon Nicole Ash

Deepak Gandhi

Chavez Vargas Carlos

Methods and systems for rotationally aligning a commissure of a prosthetic heart valve with a commissure of a native valve are disclosed. In some examples, a delivery apparatus can include a first shaft configured to rotate around a central longitudinal axis of the delivery apparatus to rotationally align a prosthetic valve mounted on the delivery apparatus with native anatomy, a second shaft extending through the first shaft and having a distal end portion extending distally beyond a distal end portion of the first shaft, an inflatable balloon coupled to the distal end portion of the first shaft, and a distal shoulder mounted on the distal end portion of the second shaft and arranged within a distal end portion of the balloon. The distal shoulder comprises a base portion and a flared portion that extends radially outward from the base portion, and a radiopaque marker is disposed on the flared portion.

Methods and systems for aligning a commissure of a prosthetic heart valve with a commissure of a native valve

Apparatuses, systems, and methods for crimping prosthetic implants onto a delivery apparatus are disclosed. In some examples, a support body for a prosthetic heart valve can comprise a first portion comprising an alignment device configured to couple with a crimping device, and a second portion comprising a support surface that tapers from a wider end disposed adjacent the first portion to a narrower end, where the support surface is configured to receive the prosthetic heart valve thereon and hold one or more leaflets of the prosthetic heart valve in an open position. The support body can further comprise a central channel extending through the first portion and the second portion, the central channel configured to receive a delivery apparatus for the prosthetic heart valve therethrough.

Systems and methods for crimping and device preparation

Methods and systems for attaching a radiopaque marker to a prosthetic heart valve to indicate a location of a commissure of the prosthetic heart valve are disclosed. As one embodiment, a prosthetic heart valve can include a frame including a plurality of struts forming a plurality of cells of the frame arranged between an inflow end and an outflow end of the frame, a plurality of leaflets arranged within the frame, at least one commissure comprising an attachment member arranged across a selected cell of the plurality of cells of the frame and attached to struts of the frame forming the selected cell, and commissure tabs of two adjacent leaflets coupled to the attachment member, and a radiopaque marker arranged on the attachment member of the commissure. The marker is configured to indicate a location of the commissure of the prosthetic heart valve.

Commissure marker for a prosthetic heart valve

An improved elastomeric pump for an infusion assembly. The pump includes a generally cylindrical mandrel body with first end, an opposed second end, a length, an outer diameter corresponding to a first radius (R), a central bore extending through the length, a first port extending from the outer diameter to the bore to provide a fluid passageway, a fill port and an exit port in fluid communication with the bore. The pump includes an inflatable elastomeric tube disposed concentrically about the mandrel, the tube being sealingly secured on the mandrel near the respective ends of the tube and having an original inner diameter that corresponds to a second radius (r) so that it approximately matches the outer diameter of the mandrel (R), a length (L) less than the length of the mandrel, a wall thickness (t) such that:(0.4225&#xd7;)&#x3c;&#x2264;(0.660&#xd7;).

Inflatable elastomeric pump for an infusion assembly

A patient controlled liquid drug administration device providing either or both of a continuous flow of a liquid drug, as well as successive boluses thereof, to be self-administered by a patient while allowing delivery of only full bolus volumes. The device includes a reciprocating pump defining a closed internal reservoir having a fixed first wall, and a second, flexible wall that is axially movable in relation to the fixed wall between reservoir-full and reservoir-empty positions. A lock is connected to a push button that activates a plunger of the pump. The lock has a first position preventing the push button from being depressed when the push button is in an extended position and the plunger is in a reservoir-empty position and a second position permitting the push button to be depressed when the push button is in an extended position and the plunger is in a reservoir-full position.

Large-volume bolus patient controlled drug administration device with lock-out

Flow control device knob with indicia

An improved elastomeric pump for an infusion assembly. The pump includes a generally cylindrical mandrel body with first end, an opposed second end, a length, an outer diameter corresponding to a first radius (R), a central bore extending through the length, a first port extending from the outer diameter to the bore to provide a fluid passageway, a fill port and an exit port in fluid communication with the bore. The pump includes an inflatable elastomeric tube disposed concentrically about the mandrel, the tube being sealingly secured on the mandrel near the respective ends of the tube and having an original inner diameter that corresponds to a second radius (r) so that it approximately matches the outer diameter of the mandrel (R), a length (L) less than the length of the mandrel, a wall thickness (t) such that:(0.4225&#xd7;)&#x3c;&#x2266;(0.660&#xd7;).

Flow control device with indicia

Flow control device knob

Growing community of inventors

Aliso Viejo, CA, United States of America

Quang Ngoc Vu