The General Hospital Corporation

Quan Zhang

Gary Strangman

David Alan Boas

Yuanting Zhang

Ang Li

A system and a method is provided for assessing motion of a biological tissue of a subject including one or more superficial biological layers and a targeted biological layer. A perturbation unit provide an optical perturbation to the one or more superficial biological layers. An optical signal generator transmits optical signals at one or more near-infrared wavelengths. An optical signal receiver acquires a set of optical signal data preceding, during, or following the optical perturbation at a first acquisition time relative to the optical perturbation. A signal processor determines, using the set of optical signal data, a set of optical characteristics and separates, using the set of optical characteristics, a target optical signal. The signal processor generates a report indicative of a movement of the targeted biological tissue within the subject. The movement of the targeted biological layer is calculated using the target optical signal.

System and method for non-invasive, intracranial brain motion monitoring

A system and a method is provided for assessing motion of a biological tissue of a subject including one or more superficial biological layers and a targeted biological layer. An optical perturbation is introduced within the one or more superficial biological layers but not within the targeted biological layer. A set of optical signal data is acquired preceding, during, or following the optical perturbation and, using the set of optical signal data, a set of optical characteristics is determined that is representative of light transiting the biological layers. Using the set of optical characteristics and a model of the biological layers, a target optical signal consistent with a target biological layer is separated and a movement of the desired biological tissue is determined using the target optical signal.

A system and method for measuring and monitoring blood pressure is provided. The system includes a wearable device and a tonometry device coupled to the wearable device. The Tonometry device is configured to compress a superficial temporal artery (STA] of a user. A sensor pad is attached to the wearable device adjacent the tonometry device. A blood pressure sensor is integrated within the sensor pad for continuous, unobtrusive blood pressure monitoring.

System for measuring and monitoring blood pressure

An electro-optical system, apparatus, and method allow long-term, ambulatory measurements to be made on a patient using light transmitted into the patient and resulting light received from the patient.

Electro-optical system, apparatus, and method for ambulatory monitoring

A system for obtaining a resultant image and a method to utilize the same are provided. In particular, first and second images of a subject or a portion of the subject are obtained. The first image includes a first portion of the subject and a second portion of the subject, and each of the first image and the second image are different types of images. A first probability that the first portion has a contrast which is greater than a predetermined contrast and a second probability that the second portion has a contrast which is greater than the predetermined contrast then is determined using the second image. For example, the second probability is greater than the first probability. Moreover, the first and second portions of the first image are reconstructed to generate the resultant image. Specifically, the first portion is reconstructed based on the first probability and the second portion is reconstructed based on the second probability.

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Winchester, MA, United States of America

Quan Zhang