Novartis Ag

Delta Electronics (shanghai) Co., Ltd

Irm LLC

Huawei Technologies Co., Limited

Lhotse Bio, Inc

Chinese Academy of Sciences

Shanghai Haihe Pharmaceutical Co., Ltd.

Shanghai Jemincare Pharmaceuticals Co., Ltd.

Jiangxi Jemincare Group Co., Ltd.

Haihe Biopharma Co., Ltd.

Qiong Zhang

Daniel J Poon

Martin Sendzik

Lei Li

Ling Li

Sabina Pecchi

Long Wang

Yuan Mi

Wei Qi

Hailong Zhang

Keith Bruce Pfister

Shenlin Huang

Mika Lindvall

Zuosheng Liu

Jianguang Zhou

Paul A Renhowe

Qiang Ding

Xianming Jin

John Tellew

Guisong Huang

Nathanael Schiander Gray

Pingda Ren

Wei Huang

Pamela Ann Albaugh

Jian Ding

Yi Chen

Cynthia Shafer

Shifeng Pan

Meiyu Geng

Aaron Matthew Smith

Yongqin Wan

Xing Wang

Guobao Zhang

Yongping Xie

Timothy D Machajewski

Hui Lei

Haizhen Zhang

Min Huang

Yahong Xiong

Donald Karanewsky

Chengzhi Zhang

Hui Li

Lin Li

Biao Wang

Chao Ma

Xichen Lin

Zhengtian Yu

Xiang-Ju Justin Gu

Yongfeng Sun

Ho Man Chan

Man Zhang

Jeff Xianming Jin

Zilin Huang

Kehao Zhao

Wooseok Han

Xiaojing Michael Wang

Yue Pan

Vivek Rauniyar

Patrick Lee

Zhongcheng Min

Yu Ding

Ji Yue (Jeff) Zhang

Jeffrey T Bagdanoff

Qun Jiang

Xiang Kou

Shejin Zhu

Xia Wang

Zhongwang Yang

Abran Q Costales

Ji Yue Zhang

Zheng Chen

Ichiro Umemura

Taebo Sim

Carlos Garcia-Echeverria

Jiqing Jiang

Shuli You

Gregory B Chopiuk

Jianbiao Peng

Michael Allen Hanson

Xingnian Fu

Zhongmiao Xu

Greg Chopiuk

Yongjin Xu

William R Antonios-McCrea

Maureen McKenna

Keiichi Masuya

Ruo W Steensma

Haibing Guo

Xiang Hu

Takanori Kanazawa

Naoko Matsuura

Osamu Ohmori

Yanyan Shen

Wei Cheng

Takahiro Miyake

Shuchun Guo

Eiji Kawahara

Andrew Jennings

Xuxing Chen

This application discloses a database system update method, applied to a database including a first node, a second node, and a shared storage device. The method includes: The first node sends a first instruction to the second node, where the first instruction is used to request storage location information of first data in the shared storage device, and the first data is data transferred by the second node to the first node for processing; and the first node obtains first information sent by the second node, and obtains mapping information from the shared storage device based on the first information, where the mapping information indicates a storage location of the first data in the shared storage device. The method is used to improve update efficiency of the database system, and ensure that different nodes can simultaneously process different data in a shared storage device.

Database system update method and related apparatus

The present disclosure provides LPA antagonists, as well as pharmaceutical compositions comprising the compounds disclosed herein. Also provided are methods for treating LPA-associated diseases, disorders, and conditions.

Compounds and compositions for treating conditions associated with LPA receptor activity

A method for replaying a log on a data node, a data node, and a database system are described. The method is used to improve a log replay speed, and includes: the data node obtaining a plurality of logs, wherein the plurality of logs includes at least one transaction commit log and at least one page operation log; and a first thread of a plurality of threads replaying the at least one page operation log, and a same second thread replaying all page operation logs including an operation on a same page. As such, log replay progress does not need to be synchronized between threads. A process in which the first thread replays the transaction commit log is independent of a process in which at least one second thread replays the at least one page operation log.

Method for replaying log on data node, data node, and system

A compound of Formula (I), or a pharmaceutically acceptable salt thereof, is provided that has been shown to be useful for treating a PRC2-mediated disease or disorder: wherein R, R, R, R, R, and n are as defined herein.

Triazolopyrimidine compounds and uses thereof

The invention provides an indolizine compound represented by formula I or a pharmaceutically acceptable salt thereof, a preparation method and a use thereof. The indolizine compound has an inhibitory effect on wild-type and/or mutant EZH2 or EZH1, and is expected to be developed into a novel drug for anti-tumor or for the treatment of autoimmune diseases. 

Indolizine compounds, preparation method and use thereof

A compound represented by formula (I), an optical isomer thereof and a pharmaceutically acceptable salt thereof, as well as an application of said compound as an FXIa inhibitor. 

Tricyclic compound, preparation method therefor and use thereof

The invention relates to a compound of formula (I): wherein variables are as defined in the specification. The compound is an inhibitor of an ERK kinase, e.g. ERK1 and/or ERK2 kinase. The invention also relates to the use of the compound and a method for preparing the compound, and a pharmaceutical composition containing the compound.

Compound having ERK kinase inhibitory activity and use thereof

A compound of Formula (IA), or a pharmaceutically acceptable salt thereof, is provided that has been shown to be useful for treating a PRC2-mediated disease or disorder: wherein A, R, Rand Rare as defined herein.

Triazolopyridine compounds and uses thereof

A compound of Formula (IA), or a pharmaceutically acceptable salt thereof, is provided that has been shown to be useful for treating a PRC2-mediated disease or disorder: wherein A, R, R, R, and Rare as defined herein.

Imidazolepyridine compounds and uses thereof

The present invention provides a compound of Formula (I) or a salt thereof; and therapeutic uses of these compounds. The present invention further provides pharmaceutical compositions comprising these compounds, and compositions comprising these compounds with a therapeutic co-agent.

Aminoheteroaryl benzamides as kinase inhibitors

Disclosed herein is a DC/DC power supply apparatus, which includes a plurality of power boards, a control board and a main board. The plurality of power boards are coupled in parallel with one another, and each power board includes a carrier circuit board and a power device disposed on the carrier circuit board. The control board includes a feedback control circuit and a PWM generator circuit; the feedback control circuit is configured to receive one or more feedback signals from the power boards; the PWM generator circuit outputs a PWM control signal to the power boards based on the feedback signal. The main board is electrically coupled to the power boards and the control board.

Direct current to direct current power supply apparatus

Growing community of inventors

Shanghai, China

Qiong Zhang