International Business Machines Corporation

Wuxi Biologics Ireland Limited

Wuxi Biologics (shanghai) Co., Ltd.

Qiong Wu

Jing Li

Yong Sen Zheng

Zhong Fang Yuan

Tong Liu

Yi Chen Zhong

Dan Wu

Yu Pan

Li Juan Gao

Provided are novel fully human monoclonal antibodies that bind to human LAG-3. It also provides the methods of hybridoma generation using humanized rats, the nucleic acid molecules encoding the anti-LAG-3 antibodies, expression vectors and host cells used for the expression of anti-LAG-3 antibodies. The invention further provides the methods for validating the function of antibodies in vitro. The antibodies of invention provide a potent agent for the treatment of multiple cancers via modulating human immune function.

Monoclonal antibody against human LAG-3, method for preparing the same, and use thereof

A method, system, and computer program product for segmenting and processing documents for optical character recognition is provided. The method includes receiving a document and detecting different types of text data. The document is divided into a plurality of text regions associated with the different types of said text data. Optical noise is removed from each text region and differing optical character recognition software code is selected for application to each text region. The differing optical character recognition software code is executed with respect to each text region resulting in extractable computer readable text located within each said text region.

Optical character recognition segmentation

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Shanghai, China

Qiong Wu