Jiangnan University

Qingmin Kong

Gang Wang

Hao Zhang

Jianxin Zhao

Qixiao Zhai

Wenwei Lu

Bo Yang

Shumao Cui

Bingyong Mao

Xi Liang

The present disclosure discloses multifunctional lactobacilli capable of relieving a toxic effect of perfluorooctanoic acid (PFOA) and use thereof, and belongs to the technical field of microorganisms.CCFM1051,CCFM1052 andCCFM1053 of the present disclosure have high adsorption effect on PFOA, can significantly relieve liver oxidative stress damage and serum biochemical indicators caused by PFOA, spleen atrophy caused by PFOA exposure, imbalance of intestinal microorganisms caused by PFOA exposure and metabolic disorder of intestinal flora caused by PFOA exposure, significantly increase the content of acetic acid and propionic acid in the intestinal tract, increase the fecal water content and decrease first black stool defecation time of mice with constipation, improve proliferation and MafA gene expression of INS-1 cells under high glucose, have the potential to relieve PFOA-related diabetes, reduce occurrence of liver diseases, metabolic diseases and potential carcinogenicity, and have broad use prospects.

Multifunctionalcapable of relieving PFOA toxic effects and application thereof

Growing community of inventors

Wuxi, China

Qingmin Kong