China Pharmaceutical University

Nanjing Medical University Affiliated Brain Hospital

Qingjiang Liao

Qidong You

Hua Xiang

Hong Xiao

Yao Yao

Xiaobo Li

Wei Zhao

Lei Qian

Renling Ma

Tianlin Wang

Isoflavone fatty acid ester derivatives of formula (I) or (II), the preparation method thereof and the pharmaceutical compositions containing such compounds are disclosed. The uses of such compounds in preparation of medicaments for preventing or treating hyperlipidemia, obesity or type II diabetes are also disclosed.

Isoflavone fatty acid ester derivatives, preparation method and pharmaceutical uses thereof

Indenoisoquinolinone derivatives (I), the manufacturing method and the medical use thereof, which belong to pharmaceutical chemistry and organic chemistry field, are disclosed. These compounds can be used for treating several medical symptoms related to postmenopausal syndrome, uterine fibers deterioration and aortic smooth muscle cells proliferation, especially ER-(+) depend breast cancer. Meanwhile, these compounds can also be used for treating glioma and lung cancer, and have inhibiting effect on tumor metastasis effect on tumor metastasis.

Indenoisoquinolinone derivatives, manufacturing method and medical use thereof

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Jiangsu, China

Qingjiang Liao